Comprehensive improvement and prevention of arsenic toxicity by the detoxication via acceleration of excretion from body and the detoxifying of arsenic in drinking water.
Comprehensive improvement and prevention of arsenic toxicity by the detoxication via acceleration of excretion from body and the detoxifying of arsenic in drinking water.
批准号:
20406014
负责人:
YOSHIDA Takahiko
金额:
$10.82万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
用原生产的西兰花(B)粉处理仓鼠和健康志愿者,评估砷的代谢和排泄。其次,对环境砷的脱毒过程进行了研究。B粉可促进尿中砷的甲基化和排泄。同时,对人体必需矿物质的剥夺和化学值的异常均无明显影响。在维生素B12的作用下,无机砷在还原条件下有可能转化为砷的无毒形态。我们的研究结果将有助于制定综合对策,改善症状,预防砷污染地区的新受害者。
英文摘要
Originally manufactured broccoli (B) powder was treated to hamster and healthy volunteer and evaluated metabolism and excretion of arsenic. Secondly, detoxifying process of environmental arsenic was investigated. B powder enhanced methylation and excretion into urine of arsenic. At the same time, there was no obvious effect on the deprivation of essential minerals and the abnormalities of chemical values. Inorganic arsenic was possible to convert to arsenobataine, innoxious arsenic form, under reductive condition with vitamin B12 action. Our results will be helpful for setting up the comprehensive countermeasures, improvement of symptoms and prevention of new victims among the arsenic contaminated area.
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無機ヒ素のメチル化に対するスルフォラファンの効果
萝卜硫素对无机砷甲基化的影响
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[鶴見麻依, 山内博, 吉田貴彦, 伊藤俊弘]
通讯作者:
伊藤俊弘
無機ヒ素のメチル化と生体防御反応に対するスルフォラファンの効果
萝卜硫素对无机砷甲基化和生物防御反应的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[伊奈孝一郎, 林登志雄, 内村彩子]
通讯作者:
内村彩子
無機ヒ素のメチル化に対する機能性食品(ブロッコリースプラウト)の効果と生体防御と
功能性食品(西兰花芽)对无机砷甲基化和生物防御的影响
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Nakatsu Y, Kotake Y, Takai N, Ohta S., 内村彩子]
通讯作者:
内村彩子
機能性食品(ブロッコリースプラウト)を用いた無機ヒ素のメチル化に関する研究;1)尿中メチル化ヒ素の動態
利用功能食品(西兰花芽)进行无机砷甲基化研究1)尿甲基化砷动态;
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[鶴見麻依, 山内博, 吉田貴彦, 伊藤俊弘]
通讯作者:
伊藤俊弘
無機ヒ素のメチル化と酸化的DNA損傷に対するブロッコリースプラウトの効果について
西兰花芽对无机砷甲基化和氧化DNA损伤的影响
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[鶴見麻依, 山内博, 吉田貴彦, 伊藤俊弘]
通讯作者:
伊藤俊弘
共 9 条
Immunomodulating effects on nano size particles which used as food additives.
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批准号:25670309
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.25万
-
财政年份:2013
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负责人:YOSHIDA Takahiko
-
依托单位:
Theory of local index and geometric quantization
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批准号:24540095
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.25万
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财政年份:2012
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负责人:YOSHIDA Takahiko
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依托单位:
A localization technique for indices of Dirac-type operators and singular Lagrangian fibrations
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批准号:22740046
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.0万
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财政年份:2010
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负责人:YOSHIDA Takahiko
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依托单位:
Local torus actions on Lagrangian fibrations
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批准号:20740029
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.0万
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财政年份:2008
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负责人:YOSHIDA Takahiko
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依托单位:
Animal experiment and clinical research on the immunological involvement in pathological formation of sick building symptoms
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批准号:18390177
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.91万
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财政年份:2006
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负责人:YOSHIDA Takahiko
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依托单位:
Developmental research of biochemical test based on the molecular biological analysis of sick house syndrome
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批准号:16390167
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.09万
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财政年份:2004
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负责人:YOSHIDA Takahiko
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依托单位:
The elucidative research of the factors which regulate the symptoms of chronic arsenic poisoning
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批准号:15406022
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.3万
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财政年份:2003
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负责人:YOSHIDA Takahiko
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依托单位:
Study of the relation between the modulations of allergic response and the sick house syndrome caused by indoor air pollutants
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批准号:13470078
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.09万
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财政年份:2001
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负责人:YOSHIDA Takahiko
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依托单位:
Study on bio-molecular analysis of occupational arsenic poisoning and on the prevention of arsenic poisoning
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批准号:11691220
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$4.35万
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财政年份:1999
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负责人:YOSHIDA Takahiko
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依托单位:
Study on health disorders by mix exposure of arsenic and fluoride in China via drinking water
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批准号:10470099
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$4.35万
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财政年份:1998
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负责人:YOSHIDA Takahiko
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依托单位:
Analysis of modification of allergic responses observed in formaldehyde exposed mice
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批准号:07670411
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.58万
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财政年份:1995
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负责人:YOSHIDA Takahiko
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依托单位:
海外基金