Comprehensive improvement and prevention of arsenic toxicity by the detoxication via acceleration of excretion from body and the detoxifying of arsenic in drinking water.

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Originally manufactured broccoli (B) powder was treated to hamster and healthy volunteer and evaluated metabolism and excretion of arsenic. Secondly, detoxifying process of environmental arsenic was investigated. B powder enhanced methylation and excretion into urine of arsenic. At the same time, there was no obvious effect on the deprivation of essential minerals and the abnormalities of chemical values. Inorganic arsenic was possible to convert to arsenobataine, innoxious arsenic form, under reductive condition with vitamin B12 action. Our results will be helpful for setting up the comprehensive countermeasures, improvement of symptoms and prevention of new victims among the arsenic contaminated area.