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Functional characterization of novel proteins involved in mitochondrial dynamics

Functional characterization of novel proteins involved in mitochondrial dynamics
参与线粒体动力学的新型蛋白质的功能表征
批准号:
20770156
负责人:
NAKAMURA Nobuhiro
金额:
$2.58万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009

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中文摘要
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英文摘要
This study has demonstrated that 1) an enzymatic activity of human USP30, a novel mitochondrial deubiquitinating enzyme, is required for maintenance of mitochondrial morphology, and 2) mouse GGNBP1 is highly expressed in spermatogenic cells and induces Drp1-dependent mitochondrial fragmentation. These results provide better understand of the molecular mechanism of mitochondrial dynamics.
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Regulation of mitochondrial morphology by USP30
USP30 对线粒体形态的调节
DOI: --
发表时间: 2008
期刊: a deubiquitinating enzyme present in the mitochondrial outer membrane. Molecular Biology of the Cell 19(5)
影响因子: --
作者: [Nakamura N, Hirose S]
通讯作者: Hirose S
DOI: 10.1095/biolreprod.108.074013
发表时间: 2009-04-01
期刊: BIOLOGY OF REPRODUCTION
影响因子: 3.6
作者: [Aihara, Takeshi, Nakamura, Nobuhiro, Hirose, Shigehisa]
通讯作者: Hirose, Shigehisa
DOI: 10.1016/j.ydbio.2009.02.026
发表时间: 2009-05-01
期刊: DEVELOPMENTAL BIOLOGY
影响因子: 2.7
作者: [Esaki, Masahiro, Hoshijima, Kazuyuki, Hirose, Shigehisa]
通讯作者: Hirose, Shigehisa
DOI: 10.1091/mbc.e07-11-1103
发表时间: 2008-05-01
期刊: MOLECULAR BIOLOGY OF THE CELL
影响因子: 3.3
作者: [Nakamura, Nobuhiro, Hirose, Shigehisa]
通讯作者: Hirose, Shigehisa
8
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    • 项目类别:
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