Effect of bisphosphonate on tooth replantation.

双膦酸盐对牙齿再植的影响。

• 批准号: 20791392
• 负责人: ENDO Makoto
• 金额: $ 1.5万
• 依托单位: Iwate Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20791392/
• 关键词: 歯牙再植; ビスホスホネート; 破骨細胞; 歯芽再植

Control group that soaked dentin board in distilled water for 20 minutes,that soaked dentin board in EDTA solution for 20 minutes,that soaked dentin board in sodium fluoride for 20 minutes,that soaked pamidronate disodium as bisphosphonate for 20 minutes,It divides into the group that soaked the dentin board in the pamidronate disodium for 24 hours,And the Osteoclast Precursor Cell was cultured for 14 days, and the observation and the measurement of Resorption lacuna were done.It was shown that there was dentin Absorption controlling effect equal with sodium fluoride in Pamidronate Disodium.Additionally, osteoclasts was not formed in Pamidronate Disodium in Dental cementum.

对照组用蒸馏水浸泡牙本质板20 min，EDTA溶液浸泡牙本质板20 min，氟化钠浸泡牙本质板20 min，帕米膦酸二钠浸泡牙本质板20 min，再分为帕米膦酸二钠浸泡牙本质板24 h组，破骨细胞前体细胞培养14 d，结果表明，帕米膦酸二钠缓释剂对牙本质吸收有与氟化钠相当的抑制作用，且在牙骨质中无破骨细胞形成。

项目成果

The effect of bisphosphonate for osteoclastic resorption on dentin and cementum

双膦酸盐对牙本质和牙骨质破骨细胞吸收的影响

• 发表时间: 2008
• 作者: Endo;M.;Kikuchi;M.;Terata;R.;Kubota. M.
• 通讯作者: Kubota. M.

The effect of bisphosphonate for osteoclastic resorption on dentin and cementum.

双膦酸盐对牙本质和牙骨质破骨细胞吸收的影响。

• 发表时间: 2008
• 作者: Endo;M.;Kikuchi;M.;Terata;R.;Kubota;M.
• 通讯作者: M.