Effect of bisphosphonate on tooth replantation.

对照组分别用蒸馏水浸泡牙本质板20分钟、用EDTA溶液浸泡牙本质板20分钟、用氟化钠浸泡牙本质板20分钟、用帕米膦酸二钠作为双磷酸盐浸泡牙本质板20分钟，分为帕米膦酸二钠浸泡牙本质板24小时组，培养破骨细胞前体细胞14天，观察并测定吸收空隙。结果表明，帕米膦酸二钠具有与氟化钠相当的牙本质吸收控制作用。此外，在牙骨质中，帕米膦酸二钠不能形成破骨细胞。

Control group that soaked dentin board in distilled water for 20 minutes,that soaked dentin board in EDTA solution for 20 minutes,that soaked dentin board in sodium fluoride for 20 minutes,that soaked pamidronate disodium as bisphosphonate for 20 minutes,It divides into the group that soaked the dentin board in the pamidronate disodium for 24 hours,And the Osteoclast Precursor Cell was cultured for 14 days, and the observation and the measurement of Resorption lacuna were done.It was shown that there was dentin Absorption controlling effect equal with sodium fluoride in Pamidronate Disodium.Additionally, osteoclasts was not formed in Pamidronate Disodium in Dental cementum.