Effect of bisphosphonate on tooth replantation.

对照组用蒸馏水浸泡牙本质板20 min，EDTA溶液浸泡牙本质板20 min，氟化钠浸泡牙本质板20 min，帕米膦酸二钠浸泡牙本质板20 min，再分为帕米膦酸二钠浸泡牙本质板24 h组，破骨细胞前体细胞培养14 d，结果表明，帕米膦酸二钠缓释剂对牙本质吸收有与氟化钠相当的抑制作用，且在牙骨质中无破骨细胞形成。

Control group that soaked dentin board in distilled water for 20 minutes,that soaked dentin board in EDTA solution for 20 minutes,that soaked dentin board in sodium fluoride for 20 minutes,that soaked pamidronate disodium as bisphosphonate for 20 minutes,It divides into the group that soaked the dentin board in the pamidronate disodium for 24 hours,And the Osteoclast Precursor Cell was cultured for 14 days, and the observation and the measurement of Resorption lacuna were done.It was shown that there was dentin Absorption controlling effect equal with sodium fluoride in Pamidronate Disodium.Additionally, osteoclasts was not formed in Pamidronate Disodium in Dental cementum.