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Research on defense of neurodegenerative disease by nutritional content

Research on defense of neurodegenerative disease by nutritional content
通过营养成分防御神经退行性疾病的研究
批准号:
20700614
负责人:
TADA Osamu
金额:
$2.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009

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中文摘要
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英文摘要
Previously, it is known that the neuronal cell of the hippocampus drops out selectively by whole brain ischemia for a short time. It is clear that triggered by the activation of the intracellular protease such as calpain, cathepsins B, and L in this neuronal cell death. In the present study, the protective activity in the neuronal cell death at in vivo by the protein and the amino acid nutrition was examined by rat's ischemia. As a result, cysteine intake was demonstrated to inhibit the activation of the intracellular proteases, but even the maintenance of the nerve tissue at the histological analysis and the maintenance of the memory and the learning ability were not able to find the effect.
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