The molecular mechanisms of chronic exercise to improve the developmental disorders
The molecular mechanisms of chronic exercise to improve the developmental disorders
批准号:
21500642
负责人:
NAKANO Hiroshi
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
丙基硫氧嘧啶(PTU)在发育过程中引起的甲状腺激素不足导致发育障碍,如较少的焦虑、运动障碍以及学习和记忆障碍。另一方面,跑步运动训练在新生儿期暴露于甲状腺功能低下的受试者的脑组织BDNF水平的变化中增强了空间学习。
英文摘要
Propylthiouracil(PTU)-induced thyroid hormone insufficiency during development has caused developmental disorder, e. g. less anxiety, motor impairment, and learning and memory impairment. On the other hand, running exercise training has enhanced spatial learning in alterations of brain BDNF level in subjects exposed to hypothyroid in the neonatal period.
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Effects of exercise training on spatial learning and serum brain-derived neurotrophic factor in PTU-exposed rat
运动训练对PTU暴露大鼠空间学习和血清脑源性神经营养因子的影响
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[高橋瑠璃, 大竹まり子, 森鍵祐子, 鈴木育子, 細谷たき子, 叶谷由佳, 大貫義人, 小林淳子, Nakano H]
通讯作者:
Nakano H
甲状腺ホルモン撹乱による発達障害モデルラット
甲状腺激素紊乱所致发育障碍模型大鼠
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[大竹まり子, ほか10名, 船瀬広三, 中野裕史]
通讯作者:
中野裕史
空間記憶保持に及ぼす走運動の影響
跑步运动对空间记忆保留的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[藤井智子, 内貴猛, 林紘三郎, 中野裕史]
通讯作者:
中野裕史
恐怖刺激を伴う運動は発達障害の症状を悪化させる
伴随可怕刺激的运动会加重发育障碍的症状
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[佐久間夕美子, ほか10名, 守下卓也, 中野裕史]
通讯作者:
中野裕史
幼児・児童の健康問題を考える―環境変化と脳機能の視点より―
考虑婴儿和儿童的健康问题——从环境变化和大脑功能的角度——
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[佐久間夕美子, 佐々木晶代, 瀧波敦, 清石幸子, 森鍵祐子, 鈴木育子, 細谷たき子, 小林淳子, 叶谷由佳, 大貫義人, 佐藤千史, 中野裕史]
通讯作者:
中野裕史
共 6 条
Empirical study for bringing up ability to solve a problem by applying a having learned matter
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批准号:22500798
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2010
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负责人:NAKANO Hiroshi
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依托单位:
Proteomics analysis of a mechanism of sinusoidal endothelial cell injury after receiving oxaliplatin-based chemotherapy in colorectal liver metastases.
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批准号:22591509
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2010
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负责人:NAKANO Hiroshi
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依托单位:
Development of a Context-aware Authoring Tool for Simulation Learning Materials
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批准号:21500946
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2009
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负责人:NAKANO Hiroshi
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依托单位:
Cytokine Immuno-gene Therapy Against Head and Neck Squamous Cell Carcinoma
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批准号:21791632
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.66万
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财政年份:2009
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负责人:NAKANO Hiroshi
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依托单位:
Empirical study on arithmetic department class that intends understanding and use of mathematical principle.
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批准号:19500713
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2007
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负责人:NAKANO Hiroshi
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依托单位:
Therapeutic approach against surgical injury of diseased liver : Proteomics approach
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批准号:18591528
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.49万
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财政年份:2006
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负责人:NAKANO Hiroshi
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依托单位:
Modification of the Hepatic Mitochondrial Proteome in Response to Ischemic Preconditioning Following Ischemia-Reperfusion Injury of the Rat Steatotic Liver.
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批准号:16591367
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2004
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负责人:NAKANO Hiroshi
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依托单位:
Practical Approach to Teaching Scientific Fundamentals from Computer Mechanisms using Multimedia
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批准号:15606012
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2003
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负责人:NAKANO Hiroshi
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依托单位:
EFFECT OF ACETOALDEHYDE ON THE GENE EXPRESSION OF TYPE IV COLLAGENASES AND THOSE INHIBITORS IN CULTURED HUMAN ITO-CELLS
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批准号:08670613
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1996
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负责人:NAKANO Hiroshi
-
依托单位:
Research for investigating treatment of fulnilnant hepatic failure : An experimental study of auxiliary temporal partial orthotopic liver transplantation using living-donor partial liver
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批准号:08557078
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$6.27万
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财政年份:1996
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负责人:NAKANO Hiroshi
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依托单位:
Research for pathophysiology and therapeutic means of hepatic oxidatiye stress in obstructive iaundice.
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批准号:07671424
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.47万
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财政年份:1995
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负责人:NAKANO Hiroshi
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依托单位:
APPLICATION OF NEURAL NETWORK TO THE ASSESSMENT FOR THE DEGREE OF HEPATIC FIBROSIS
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批准号:06670577
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.32万
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财政年份:1994
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负责人:NAKANO Hiroshi
-
依托单位:
Basic Study on the Description of Structure of Japanese Language for Analysis and Generation of Context
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批准号:06401011
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$5.7万
-
财政年份:1994
-
负责人:NAKANO Hiroshi
-
依托单位:
STUDY OF CONSTRUCTION AND USE OF THESAURUS OF JAPANESE WORDS AS DATABASE
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批准号:04451082
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$2.18万
-
财政年份:1992
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负责人:NAKANO Hiroshi
-
依托单位:
海外基金