Studies on a novel protein promoting cell self-renewal and translation for the application of muscle anti-aging

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The human protein, named bystin, has been indicated to benecessary for self-renewal of undifferentiated cells such as stem cells and to be important for translational activation in cells, and thus has a unique property playing two distinct roles. Because the molecular mechanisms for these roles were unclear, proteinscooperating with bystin were surveyed, and novel factors were identified and analyzed. These findings are expected to lead to useful mechanisms applicable to differentiation of muscular cells, which requires cell number increase and growth.