Research for Immunotherapy of Adult T cell Leukemia(ATL)
Research for Immunotherapy of Adult T cell Leukemia(ATL)
批准号:
21590521
负责人:
HASEGAWA Hideki
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Adult T-cell Leukemia(ATL) is a refractory disease. It is suggested that the treatment resistant cancer stem cells are present in the leukemic cells population. We have attempted to identify molecules that can be a target for immunotherapy which target the cancer stem cells using a mouse model of ATL. We identified molecules that are specifically expressed on the surface of cancer stem cells of mouse ATL cells by multi TOF MASS analyzer. The molecule can be a therapeutic target of ATL.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia.
治疗引起的鼠类成人T细胞白血病中白血病发射活性的选择性丧失。
DOI:
10.1084/jem.20101095
发表时间:
2010-12-20
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
[El Hajj H, El-Sabban M, Hasegawa H, Zaatari G, Ablain J, Saab ST, Janin A, Mahfouz R, Nasr R, Kfoury Y, Nicot C, Hermine O, Hall W, de Thé H, Bazarbachi A]
通讯作者:
Bazarbachi A
MOLECULAR CHAPERON INHIBITOR-BASED TREATMENT AGAINSTATL : ITS IN VITRO AND IN VIVO EVALUATION
基于分子伴侣抑制剂的针对STATL的治疗:体外和体内评估
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Hidekatsu Iha, Emi Ikebe, Akira Kawaguchi, Shinya Taguchi, Akira Nishizono, Yuetsu Tanaka, Hirofumi Sawa, Masao Ogata, Mitsuo Hori, Jun-Ichi Fujisawa, Hideki Hasegawa]
通讯作者:
Hideki Hasegawa
CXCR4アンタゴニスト(AMD3100)を用いたSCIDマウスにおける Tax トランスジェニックマウス由来腫瘍細胞の組織浸潤抑制
使用 CXCR4 拮抗剂 (AMD3100) 抑制 SCID 小鼠中 Tax 转基因小鼠来源的肿瘤细胞的组织侵袭
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[川口晶, 辻隆裕, 大場靖子, 木村享史, 相内章, 伊波英克, 緒方正男, 佐多徹太郎, 澤洋文, 長谷川秀樹]
通讯作者:
長谷川秀樹
原人T細胞性白血病(ATL)モデルマウスを用いた新規治療法の試み
使用人类 T 细胞白血病 (ATL) 模型小鼠试验新的治疗方法
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Yoshida T, Saito A, Iwasaki Y, Iijima S, Kurosawa T, Katakai Y, Yasutomi Y, Reimann KA, Hayakawa T, Akari H, 長谷川秀樹]
通讯作者:
長谷川秀樹
Inhibition of the SDF-1α-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of human ATLL cells and murine lymphoblastoid cells from HTLV-I Tax transgenic mice
CXCR4 拮抗剂 AMD3100 对 SDF-1α-CXCR4 轴的抑制可抑制 HTLV-I Tax 转基因小鼠的人 ATLL 细胞和鼠类淋巴母细胞的迁移
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Kawaguchi A, Orba Y, Kimura T, Iha H, Ogata M, Tsuji T, Sata T, Okamoto T, Hall W.W., Sawa H, Hasegawa H.]
通讯作者:
Hasegawa H.
共 15 条
International Organization of Francophonie and multicultural and cultural society
-
批准号:20530456
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.0万
-
财政年份:2008
-
负责人:HASEGAWA Hideki
-
依托单位:
GaN-based Chemical Sensors and Their On-chip Integration Using Nanowire Networks
-
批准号:18360002
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.99万
-
财政年份:2006
-
负责人:HASEGAWA Hideki
-
依托单位:
Single Electron Integrated Circuits Based on A BDD Architecture Utilizing Quantum Dots Controlled by Nano-Schottky Gates
-
批准号:13305020
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$35.44万
-
财政年份:2001
-
负责人:HASEGAWA Hideki
-
依托单位:
Research and development of III-V quantum wire transistor-based logic and memory circuits operating near the quantum limit
-
批准号:12555083
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.58万
-
财政年份:2000
-
负责人:HASEGAWA Hideki
-
依托单位:
Control of Metal-Compound Semiconductor Interfaces by Formation of Nano-Scale Schottky Contacts and Its Application
-
批准号:11450115
-
项目类别:Grant-in-Aid for Scientific Research (B).
-
资助金额:$9.66万
-
财政年份:1999
-
负责人:HASEGAWA Hideki
-
依托单位:
Novel Insulated Gate Structure having Ultrathin Si Quantum Well for Realization of InP-Based Ultra High-Frequency and High-Power Devices
-
批准号:10555098
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.26万
-
财政年份:1998
-
负责人:HASEGAWA Hideki
-
依托单位:
"Realization of Schottky-limit at metal-semiconductor interfaces and its application to electron devices"
-
批准号:09450118
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.09万
-
财政年份:1997
-
负责人:HASEGAWA Hideki
-
依托单位:
"Control of surface and interfaces of nano-structures for single electron devices"
-
批准号:08247101
-
项目类别:Grant-in-Aid for Scientific Research on Priority Areas
-
资助金额:$143.3万
-
财政年份:1996
-
负责人:HASEGAWA Hideki
-
依托单位:
Developement of Contactless and Non-Destructive Capacitance-Voltage Measurement System in Ultra-High Vacuum
-
批准号:08555072
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$3.84万
-
财政年份:1996
-
负责人:HASEGAWA Hideki
-
依托单位:
Control of surface states for III-V semiconductor quantum structures and its application to novel optical devices
-
批准号:07455017
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.74万
-
财政年份:1995
-
负责人:HASEGAWA Hideki
-
依托单位:
Characterization and Control of Interaction between Quantized Energy Levels and Surface/Interface States in Compound Semiconductor Quantum Structures.
-
批准号:05452181
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.54万
-
财政年份:1993
-
负责人:HASEGAWA Hideki
-
依托单位:
A Novel Contactless and Nondestructive Measurement Method of Surface State Density on Semiconductor Free Surface, and Control of Their Surfaces
-
批准号:03452147
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.48万
-
财政年份:1991
-
负责人:HASEGAWA Hideki
-
依托单位:
A new MIS Interface Control Technology for Fabrication of High Spatial Resolution InGaAs Change Coupled Devices for Imaging
-
批准号:03555056
-
项目类别:Grant-in-Aid for Developmental Scientific Research (B)
-
资助金额:$8.7万
-
财政年份:1991
-
负责人:HASEGAWA Hideki
-
依托单位:
New Waveguides for Microwave Monolithic Integrated Circuits Using Distributed Parameter Effects of Semiconductor Carriers
-
批准号:63460115
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.22万
-
财政年份:1988
-
负责人:HASEGAWA Hideki
-
依托单位:
海外基金