Identification of the therapeutic effect of new enzyme-targeting radiosensitization treatment, KORTUC for tumor stem cells
Identification of the therapeutic effect of new enzyme-targeting radiosensitization treatment, KORTUC for tumor stem cells
批准号:
21591610
负责人:
OGAWA Yasuhiro
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Using PET-CT and MRI, the therapeutic effects of new enzyme-targeting radiosensitization treatment, KORTUC were evaluated following the treatment for breast cancer patients treated by KORTUC without any surgical procedure. CD44-positive breast cancer cells thought to be breast cancer stem cells were detected by an immunohistochemical method using biopsy specimens obtained prior to the treatment. As a results, it was concluded that KORTUC exerted fully therapeutic effect irrespective of the existence of CD44-positive tumor cells.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.3892/etm.2010.123
发表时间:
2010-09-01
期刊:
EXPERIMENTAL AND THERAPEUTIC MEDICINE
影响因子:
2.7
作者:
[Hitomi, Jiro, Kubota, Kei, Nishioka, Akihito]
通讯作者:
Nishioka, Akihito
Safety and efficacy of new enzyme targeting intraoperative radiotherapy for locally advanced pancreatic cancer
新型酶靶向术中放疗治疗局部晚期胰腺癌的安全性和有效性
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Nishioka A, Ogawa Y, Kariya S, Miyatake K, Tadokoro M, Ue H, Matsui R, Hamada N, Kubota K]
通讯作者:
Kubota K
Phase I study of intra-tumoral injection of a newly developed enzyme-targeting radiosensitizer(KORTUC)containing hydrogen peroxide…
新开发的含过氧化氢的酶靶向放射增敏剂(KORTUC)瘤内注射的 I 期研究......
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Toita T, Kato S, Ishikura S, et al, 小川恭弘]
通讯作者:
小川恭弘
癌の臨床特集酵素標的・増感放射線療法KORTUCの基礎と臨床
癌症临床专题:KORTUC、酶靶向和增敏放射治疗的基础和临床实践
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[小川恭弘, 他]
通讯作者:
他
DOI:
10.1016/j.ijrobp.2009.04.092
发表时间:
2009-10-01
期刊:
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
影响因子:
7
作者:
[Kariya, Shinji, Sawada, Ken, Ogawa, Yasuhiro]
通讯作者:
Ogawa, Yasuhiro
共 16 条
Automatic generation of the Outlines of Japanese Statutes
-
批准号:17K00460
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2017
-
负责人:OGAWA Yasuhiro
-
依托单位:
Relationship between spring water and slope failures occurred in a volcanic hillslope terrain under heavy rainfall
-
批准号:23651175
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.0万
-
财政年份:2011
-
负责人:OGAWA Yasuhiro
-
依托单位:
Statistical inflectional processing of agglutinative languages
-
批准号:22700143
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.25万
-
财政年份:2010
-
负责人:OGAWA Yasuhiro
-
依托单位:
ADAM22 localization mechanism and myelin formation at the Axon.
-
批准号:21890269
-
项目类别:Grant-in-Aid for Research Activity Start-up
-
资助金额:$1.7万
-
财政年份:2009
-
负责人:OGAWA Yasuhiro
-
依托单位:
Research of music scale of Konkiok and its history in Taisau
-
批准号:20520344
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2008
-
负责人:OGAWA Yasuhiro
-
依托单位:
Development of Machine Translation system from Japanese into Uzbek
-
批准号:18700141
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.11万
-
财政年份:2006
-
负责人:OGAWA Yasuhiro
-
依托单位:
Identification of a new apoptotic pathway of radiation-induced apoptosis of human peripheral lymphocytes
-
批准号:18591382
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.49万
-
财政年份:2006
-
负责人:OGAWA Yasuhiro
-
依托单位:
Robust Incremental Parsing based on Finite-State Approximation of Context Free Grammar
-
批准号:15300044
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.58万
-
财政年份:2003
-
负责人:OGAWA Yasuhiro
-
依托单位:
Reactive oxygen species producing site in radiation-induced apoptosis of human peripheral T cells: Involvement of lysosomal membrane destabilization
-
批准号:15591281
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2003
-
负责人:OGAWA Yasuhiro
-
依托单位:
Mechanism of radiation-induced apoptosis of human peripheral T cells
-
批准号:13670948
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2001
-
负责人:OGAWA Yasuhiro
-
依托单位:
Immunohistochemical study of expression of several proto-oncogenes in cancer tissues from patients undergoing radiation therapy
-
批准号:06670927
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.09万
-
财政年份:1994
-
负责人:OGAWA Yasuhiro
-
依托单位:
Development and clinical application of a predictive assay for radiotherapy using an immunohistochemical method
-
批准号:03670547
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1991
-
负责人:OGAWA Yasuhiro
-
依托单位:
国内基金
海外基金
登录
查看更多内容
疏肝理气解郁经验方“香山乳癌二号方”通过PI3K/AKT/mTOR通路抑制三阴性乳腺癌细胞增殖及迁移侵袭作用机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2024
-
负责人:
-
依托单位:
HP靶向及TCb化疗联合乳癌术后方在HER2阳性乳腺癌患者中的前瞻性研究
-
批准号:2024QN036
-
项目类别:省市级项目
-
资助金额:4.0万元
-
批准年份:2024
-
负责人:吴鸣远
-
依托单位:
circEMCN编码多肽EMCN-81激活STAT3/VEGF通路调控炎性乳癌血管生成促进恶性进展的机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:15.0万元
-
批准年份:2024
-
负责人:林颖
-
依托单位:
CTSK调控ACSs-乳腺癌细胞交互功能促进脂肪移植乳癌术后重建的机制研究
-
批准号:2023JJ60312
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2023
-
负责人:吴维子
-
依托单位:
吡哆醛通过影响脂肪酸代谢抑制卵巢高级别浆乳癌亲脂性转移的机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2021
-
负责人:令狐华
-
依托单位:
脑微环境因子共调控SHMT2影响一碳单位代谢促进三阴乳癌脑转移的机制研究
-
批准号:82072915
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2020
-
负责人:张剑
-
依托单位:
小乳癌边缘在体检测用超小内窥探针的光学模型及传光特性
-
批准号:61773249
-
项目类别:面上项目
-
资助金额:66.0万元
-
批准年份:2017
-
负责人:王驰
-
依托单位:
低氧诱导的氧化型ATM调节乳腺癌CAFs能量代谢重塑的机理及其促乳腺癌侵袭转移研究
-
批准号:81472476
-
项目类别:面上项目
-
资助金额:94.0万元
-
批准年份:2014
-
负责人:柳满然
-
依托单位:
miRNA-200s/205对乳癌CAF活化和活性维持促进ECM重塑及癌细胞增殖侵袭的机制研究
-
批准号:81402180
-
项目类别:青年科学基金项目
-
资助金额:23.0万元
-
批准年份:2014
-
负责人:侯懿烜
-
依托单位:
乳癌术后方对HER2阳性乳腺癌复发转移中NF-kB介导的MMPs细胞通路及其微环境的影响
-
批准号:81302974
-
项目类别:青年科学基金项目
-
资助金额:23.0万元
-
批准年份:2013
-
负责人:吴雪卿
-
依托单位: