Roles of receptors for lipid mediators in inflammation and immunity
Roles of receptors for lipid mediators in inflammation and immunity
批准号:
21390083
负责人:
YOKOMIZO Takehiko
金额:
$11.81万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
BLT1-deficient mice exhibited milder symptoms in models of osteoporosis, multiple sclerosis and spinal injury, suggesting the possible application of BLT1 antagonists in these diseases. We established BLT2-deficient mice, and found that BLT2 protects intestinal inflammation by enhancing the barrier functions of colon epithelial cells. We established a system to measure 12-HHT, a BLT2 ligand in combination of liquid chromatography and mass spectrometry.
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Identification of l2-HHT as an intrinsic ligand for BLT2 receptor
鉴定 l2-HHT 作为 BLT2 受体的内在配体
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[中村貴紀, 武川睦寛, Yokomizo T.]
通讯作者:
Yokomizo T.
生理活性脂質と受容体
生物活性脂质和受体
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[久保田祐二, 中亮介, 武川睦寛, 横溝岳彦]
通讯作者:
横溝岳彦
生化学実践問題基礎と臨床をつなぐ420題
420 个连接基础知识和临床实践的生物化学实用问题
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kurotaki D, Ichino M, Nishiyama A, Sato G, Yamamoto M, Ozato K, Tamura T, 横溝岳彦(訳)]
通讯作者:
横溝岳彦(訳)
新遺伝子工学ハンドブック(「トランスフェクション法」を執筆)
新基因工程手册(撰写《转染方法》)
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[佐伯和子, 横溝岳彦]
通讯作者:
横溝岳彦
A novel synthetic androgen receptor ligand, S42, works as a selective androgen receptor modulator and possesses metabolic effects with little impact on the prostate
一种新型合成雄激素受体配体 S42,作为选择性雄激素受体调节剂,具有代谢作用,对前列腺影响很小
DOI:
--
发表时间:
2009
期刊:
Endocrinology 150
影响因子:
--
作者:
[Ariyasu H, Nakao K, et al, Amagai M, Min L]
通讯作者:
Min L
共 42 条
Identification of GPCR binding proteins by using a novel anti-FLAG antibody and magnetic nanobeads
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批准号:23659157
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2010
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负责人:YOKOMIZO Takehiko
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依托单位:
Roles of lipid mediators and receptors in inflammation and immuni
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批准号:18390096
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.91万
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财政年份:2006
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负责人:YOKOMIZO Takehiko
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依托单位:
Roles of G-protein coupled receptors in inflammation and immunity.
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批准号:16390090
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.02万
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财政年份:2004
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负责人:YOKOMIZO Takehiko
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依托单位:
Roles of of lipid mediators in inflammatory system
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批准号:14570100
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.56万
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财政年份:2002
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负责人:YOKOMIZO Takehiko
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依托单位:
IN VIVO AND INTRACELLULAR ROLES OF LEUKOTRIENE B4 RECEPTOR.
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批准号:11670111
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:1999
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负责人:YOKOMIZO Takehiko
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依托单位:
海外基金