Objective evaluation of pain in cancer inpatients not complaining of cancer pain

无主诉癌症疼痛的癌症住院患者疼痛的客观评价

• 批准号: 21390581
• 负责人: YAMAMOTO Keiko
• 金额: $ 11.65万
• 依托单位: International University of Health and Welfare (2010-2011)Yokohama City University (2009)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21390581/
• 关键词: がん看護; がん疼痛; 心電図電位変動; 疼痛定量評価; がん性疼痛

The ultimate goal of our research is to establish a method to confirm pain relief in inpatients who do not complain of pain. Towards this goal, here we confirmed the feasibility of wavelet analysis of ECG voltage fluctuation as an objective evaluation method of pain in cancer inpatients who did complain of pain. In this pilot study, 8 inpatients with cancer pain underwent a subjective evaluation of pain using a visual analogue scale(VAS) or numerical rating scale(NRS) and subsequently an objective evaluation involving analysis of ECG voltage fluctuations. In particular, it was evaluated whether the objective method could be an effective aid in the diagnosis of the degree of pain. The power amplitudes of ECG voltage fluctuations were found to be correlated with VAS or NRS scores in the same period with pain in all 8 cancer inpatients without motion artifacts. Moreover, the power amplitudes of these fluctuations, VAS score, and NRS score were significantly reduced after administration of a rescue dose of opioid in 5 of the patients without motion artifacts. Power spectral analysis of ECG voltage fluctuations is a promising method to evaluate the degree of pain in cancer inpatients.

我们研究的最终目标是建立一种方法，以确认疼痛缓解住院患者谁不抱怨疼痛。为了达到这个目标，在这里，我们证实了心电图电压波动的小波分析的可行性，作为一个客观的评价方法疼痛的癌症住院病人谁抱怨的疼痛。在这项初步研究中，8例癌症疼痛住院患者接受了使用视觉模拟量表（VAS）或数字评定量表（NRS）的疼痛主观评价，随后进行了包括ECG电压波动分析的客观评价。特别是，评估了客观方法是否可以有效帮助诊断疼痛程度。在8例无运动伪影的癌症住院患者中，发现ECG电压波动的功率幅度与疼痛同期的VAS或NRS评分相关。此外，在5例无运动伪影的患者中，给予阿片类药物补救剂量后，这些波动的功率幅度、VAS评分和NRS评分显著降低。心电图电压波动的功率谱分析是一种很有前途的方法来评估癌症住院患者的疼痛程度。

项目成果

Continuous pain monitoring with wavelet analysis of ECG voltage fluctuation after rapid-onset opioid administration in terminal cancer inpatients

晚期癌症住院患者快速起效阿片类药物后心电图电压波动的小波分析连续疼痛监测

• 发表时间: 2012
• 作者: keik Yamamoto;Shinya Nagata
• 通讯作者: Shinya Nagata

Assessment Of Cancer Pain Using Subjective Scales And Wavelet Analysis of Electrocardiogram voltage Fluctuation

使用主观量表和心电图电压波动的小波分析评估癌痛

• 发表时间: 2012
• 作者: Hisako Nakao;Akiko Chishaki;Mami Miyazono;Yumiko Kinoshita;Maki Kanaoka;Akiko Tomioka;Chie Magota;Miyuki Ushio;Kohei Kajiwara;Keiko Yamamoto
• 通讯作者: Keiko Yamamoto

Wavelet Analysis of Ecg Potential Fluctuations Is Effective For Quantitative And Continuous Pain Monitoring In Healthy Volunteers And Cancer Inpatients

心电图电位波动的小波分析对于健康志愿者和癌症住院患者的定量和连续疼痛监测是有效的

• 发表时间: 2010
• 作者: Shinya Nagata;Keiko Yamamoto;Kunio Kasugai
• 通讯作者: Kunio Kasugai

Wavelet Analysiso of Ecg Potential luctuations is Effective for Quantitative and Continuous Pain Monitoring in Healthy Volunteers and Cancer Inpatients

心电图潜在波动的小波分析对于健康志愿者和癌症住院患者的定量和连续疼痛监测是有效的

• 发表时间: 2010
• 作者: Shinya Nagata;Keiko Yamamoto;Kunio Kasugai
• 通讯作者: Kunio Kasugai