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Biological function and gene regulation of epididymal-specific carboxylesterase (CES4)

Biological function and gene regulation of epididymal-specific carboxylesterase (CES4)
附睾特异性羧酸酯酶(CES4)的生物学功能和基因调控
批准号:
22580100
负责人:
YAMASHITA Tetsuro
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
The biological function of an epididymal-specific carboxylesterase, CES4, was studied using Ces4 knock out mouse. The metabolome analysis of epididymal cell extracts revealed that the most of the glutathione was identified as oxidative form in the epididymis of KO mouse. The expression of oxidative stress-responsive heme oxygenase-1 (HO-1) was also increased in the KO mouse tissue. These data indicated that the epididymis of KO mouse was exposed by oxidative stress.
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会议论文
Recommended nomenclature for five mammaian carboxylesterase gene families human, mouse and rat genes and proteins.
五个哺乳动物羧酸酯酶基因家族、人类、小鼠和大鼠基因和蛋白质的推荐命名法。
DOI: --
发表时间: 2010
期刊: Mamm.Genome
影响因子: --
作者: [Roger S Holmes, Tetsurou Yamashita, et al.]
通讯作者: et al.
DOI: --
发表时间: 2010
期刊: Vet.J.
影响因子: --
作者: [Miyazaki, M., Miyazaki, T., Toyonaga, M., Tsutsui, T., Taira, H., Yamashita, T., Suzuki, A.]
通讯作者: A.
ネコ尿タンパク質コーキシンと尿臭生成機構
猫尿蛋白coxin与尿臭味产生机制
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [馬場崎勝彦, 宮崎安将, Karim Minnatul, 長谷川純一, 家永里織, 山下哲郎]
通讯作者: 山下哲郎
遺伝子欠損マウスを用いた精巣特異的カルボキシルエステラーゼ(CES4)の機能解析
使用基因缺陷小鼠进行睾丸特异性羧酸酯酶 (CES4) 的功能分析
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [山下哲郎, 金成瑞穂, 松舘光人, 宮崎雅雄, 森松正美]
通讯作者: 森松正美
Research on the medical prediction of behavior of Non-Residential casualties around Shinjuku Station, and its countermeasures, in the case of Metropolitan Tokyo Earthquakes.
  • 批准号:
    22656133
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $1.64万
  • 财政年份:
    2010
  • 负责人:
    YAMASHITA Tetsuro
  • 依托单位:
Reconstruction the ward plan along with the appearance of the Personal Nursing Bases by the computerization of the medical treatment and the patient information
  • 批准号:
    17360296
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $3.75万
  • 财政年份:
    2005
  • 负责人:
    YAMASHITA Tetsuro
  • 依托单位:
Studies on the planning of the saving energy, the architectural building design and the air conditioning facilities for the prevention of the spray infection in the hospital
  • 批准号:
    14350320
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $4.8万
  • 财政年份:
    2002
  • 负责人:
    YAMASHITA Tetsuro
  • 依托单位:
Research on Patients' Privacy and Teritorry at their 4-beds room with individual territorialized area for each patient
  • 批准号:
    09650665
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $1.98万
  • 财政年份:
    1997
  • 负责人:
    YAMASHITA Tetsuro
  • 依托单位:
海外基金