Analysis of sex hormone actions in noninvasive breast carcinoma
Analysis of sex hormone actions in noninvasive breast carcinoma
批准号:
22590305
负责人:
SUZUKI Takashi
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
We aimed to characterize the estrogen functions in noninvasive breast carcinomas (DCIS), precursor lesion of the invasive carcinomas (IDC).Results of our present study have demonstrated that (1) estrogen functions in DCIS were different from those in IDC, andC-MYB, RbAp46 and survivin played important roles in DCIS, and (2) intratumoral estrogen concentration in DCIS was markedly decreased following aromatase inhibitor letrozole treatment, and the expression of a great majority of estrogen-induced genes andproliferative activity were markedly decreased following the treatment.These results suggest that estrogen is mainly produced by aromatase in DCIS, and aromatase inhibitors may potently inhibit estrogen actions in these patients.
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KLF5 in human breastcancer
KLF5 在人类乳腺癌中的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Takagi K, Miki Y, Onodera Y, 以下4名略, Suzuki T]
通讯作者:
Suzuki T
KLF5 in human breast cancer
KLF5 在人类乳腺癌中的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Takagi K, Miki Y, Onodera Y, 以下4名略, Suzuki T]
通讯作者:
Suzuki T
DOI:
10.1074/jbc.m110.156877
发表时间:
2011-01-07
期刊:
JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子:
4.8
作者:
[Oyama, Masaaki, Nagashima, Takeshi, Okada-Hatakeyama, Mariko]
通讯作者:
Okada-Hatakeyama, Mariko
Expression of the zinc finger protein (PLZF) in human breast carcinoma
锌指蛋白(PLZF)在人乳腺癌中的表达
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Takagi K, Miki Y, Onodera Y, 以下3名略, Suzuki T.]
通讯作者:
Suzuki T.
DOI:
10.1002/path.4019
发表时间:
2012-07-01
期刊:
JOURNAL OF PATHOLOGY
影响因子:
7.3
作者:
[Shibahara, Yukiko, Miki, Yasuhiro, Sasano, Hironobu]
通讯作者:
Sasano, Hironobu
共 11 条
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批准号:19K09065
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Analyses on multiple factors related to evaluation of antioxidant function of northern berries
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Development and publicizing of the simple and low-priced drop-sizing system for dispersive two-phase flows utilizing an image sensor
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Non-invasive quantitative in vivo optical imaging of cerebral blood flow and metabolism
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Research on a system supporting visually impaired students in learning science and image-creation of scientific phenomena
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批准号:24501163
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资助金额:$2.58万
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财政年份:2012
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The research of acoustic diagnosis and noninvasive therapy for intractable pneumothorax
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批准号:23659307
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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Research on the rapid measurement of stability of a refrigerant having low global warming potential
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2010
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依托单位:
Perspectives on the Chinese Political Regime on Taisho Period
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批准号:20730110
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$0.58万
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财政年份:2008
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依托单位:
Analysis for nonlinear critical phenomena described by mean field equations
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批准号:20340034
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资助金额:$8.57万
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财政年份:2008
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依托单位:
Development of novel multiferroics with stress field cross correlation
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批准号:20340093
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资助金额:$12.15万
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Motor control method using kinetic energy storage for noiseless image in MR image guided robotic surgery
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批准号:20700413
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.83万
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Analysis of androgen actions in human breast carcinoma
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资助金额:$2.83万
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Molecular characterization of a novel cyanide-sensitive quinol oxidase of Trypanosoma cruzi
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Basic Study for Developing The Efficient Production Method of Fine Uniform Particles
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Mechanism and novel functions of pressure-induced superconductor-insulator transition in chalcogenide spinels
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批准号:17340113
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Mathematical Study of the Nonlinear Partial Differential Equations Arising in the Statistical Mechanics
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批准号:16340047
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依托单位:
Estrogenic actions in human breast carcinoma : analyses for expression and regulation of the estrogen responsive genes
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项目类别:Grant-in-Aid for Scientific Research (C)
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Structure of parainfluenza virus receptor binding region and control of the virus infection
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批准号:14570270
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Superconductor -Insulator Transition in Cuprates
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批准号:13440114
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Mathematical Analysis to Nonlinear Partial Differential Equations in Mathematical Science and Its Applications
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海外基金