Analysis of T helper (Th) cell responses in immune complex nephritis with Th1/Th2/Th17 dominant mice
Analysis of T helper (Th) cell responses in immune complex nephritis with Th1/Th2/Th17 dominant mice
Th1/Th2/Th17 优势小鼠免疫复合物肾炎中辅助性 T (Th) 细胞反应分析
批准号：
22590876
负责人：
YOH Keigyou
金额：
$2.75万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2010
资助国家：
日本
项目状态：
已结题
起止时间：
2010 至 2012
中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
To clarify the roles of helper T cell in immune complex glomerulonephritis, we induced experimental immune complex glomerulonephritis in Th1/2/17 dominant transgenic mice. Th17 dominant transgenic mice showed higher volume of proteinuria than other mice, and developed crescentic glomerulonephritis. These results suggested that Th17 might play an important role in the development of immune complex glomerulonephritis.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Overexpression of RORγt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice
CD2启动子控制下的RORγt过表达诱导转基因小鼠多克隆浆细胞增多和自身抗体产生
CD2启动子控制下的RORγt过表达诱导转基因小鼠多克隆浆细胞增多和自身抗体产生
DOI：
10.1002/eji.201142250
发表时间：
2012
期刊：
Eur J Immunol
影响因子：
5.4
作者：
[Yoh K, Morito N, Ojima M, Shibuya K, Yamashita Y, Morishima Y, Ishii Y, Kusakabe M, Nishikii H, Fujita A, Matsunaga E, Okamura M, Hamada M, Suto A, Nakajima H, Shibuya A, Yamagata K, Takahashi S]
通讯作者：
Takahashi S
A novel mouse model of diabetic nephropathy : MafA-deficient and beta cell-specific MafK-overexpressing hybrid transgenic
-
批准号：19590933
-
项目类别：Grant-in-Aid for Scientific Research (C)
-
资助金额：$2.83万
-
财政年份：2007
-
负责人：YOH Keigyou
-
依托单位：
The analysis of new mouse model for glomerulonephritis and an approach for Th1/Th2 cell regulation by transcription factors
-
批准号：17590819
-
项目类别：Grant-in-Aid for Scientific Research (C)
-
资助金额：$1.73万
-
财政年份：2005
-
负责人：YOH Keigyou
-
依托单位：
海外基金
