Hydrogen sulfide protects insulin-secreting cells from cell damage-Characterization of the cytoprotective effects and the molecular mechanisms-
Hydrogen sulfide protects insulin-secreting cells from cell damage-Characterization of the cytoprotective effects and the molecular mechanisms-
批准号:
22790255
负责人:
TANIGUCHI Shigeki
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The aim of this study is to characterize the cytoprotective effects of a gasotransmitter hydrogen sulfide(H_2S) and to elucidate its molecular mechanism on insulin-secreting cells. H_2S, which is endogenously produced in an inducible manner by H_2S-producing enzyme CSE, protects insulin-secreting cells against oxidative stress(occur under diabetic condition) via an anti-oxidative mechanism.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
酸化ストレス抑制により硫化水素はマウス膵β細胞を保護する
硫化氢通过抑制氧化应激来保护小鼠胰腺β细胞
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[古屋敷智之, 田中昂平, 北岡志保, 成宮周, 谷口繁生]
通讯作者:
谷口繁生
硫化水素が膵B細胞を保護する分子機序の検討
硫化氢保护胰腺B细胞的分子机制研究
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[古屋敷智之, 他, 谷口繁生]
通讯作者:
谷口繁生
膵島における硫化水素産生酵素の発現調節の種差について
胰岛中硫化氢产生酶表达调节的物种差异
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[谷口繁生, 木村俊秀, 岡本光弘, 仁木一郎, 古屋敷智之, 谷口繁生]
通讯作者:
谷口繁生
DOI:
10.1111/j.1476-5381.2010.01119.x
发表时间:
2011-03-01
期刊:
BRITISH JOURNAL OF PHARMACOLOGY
影响因子:
7.3
作者:
[Taniguchi, S., Kang, L., Niki, I.]
通讯作者:
Niki, I.
DOI:
10.1254/jphs.11r01cp
发表时间:
2011
期刊:
Journal of pharmacological sciences
影响因子:
3.5
作者:
[S. Taniguchi;I. Niki]
通讯作者:
S. Taniguchi;I. Niki
共 8 条
Construction of 3D cardiac tissue: alignment and maturation of cells, and improvement of contraction force by extensional stimulation
-
批准号:22591552
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.5万
-
财政年份:2010
-
负责人:TANIGUCHI Shigeki
-
依托单位:
New therapy for heart failure: Engineered heart tissue toward to clinical use
-
批准号:19591642
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2007
-
负责人:TANIGUCHI Shigeki
-
依托单位:
The studies of the functional significance of regenerating gene (Reg) in failing hearts.
-
批准号:16591405
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.86万
-
财政年份:2004
-
负责人:TANIGUCHI Shigeki
-
依托单位:
Embryonic stem cell (ES cell)-derived cardiomyocyte transplantation into the infarcted myocardium
-
批准号:13671401
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.37万
-
财政年份:2001
-
负责人:TANIGUCHI Shigeki
-
依托单位:
Xenotransplantation of ex vivo gene trandected cardiomyocytes
-
批准号:11470277
-
项目类别:Grant-in-Aid for Scientific Research (B).
-
资助金额:$8.13万
-
财政年份:1999
-
负责人:TANIGUCHI Shigeki
-
依托单位:
Attempt at creating donor pig by nuclear transplantation for xenotrasplantation
-
批准号:09671389
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.05万
-
财政年份:1997
-
负责人:TANIGUCHI Shigeki
-
依托单位:
海外基金