Molecular mechanism of rolling circle DNA replication of human papillomavirus
Molecular mechanism of rolling circle DNA replication of human papillomavirus
批准号:
22790443
负责人:
MATSUO Rika
金额:
$3.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
To elucidate the mechanism of DNA replication of human Papillomavirus, we searched for a factor that affects the virus DNA replication in cells. We performed ALPHA screening and identified ten tyrosine kinases that bind to HPV16 E1. We also identified peptides phosphorylated by an unknown kinase bound to E1 among a set of tyrosine kinase substrate peptides, and speculated seven kinases. Interaction between these kinases and E1 in cells and the effects of the kinases to HPV DNA replication will be tested.
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会议论文
Novel multiplexed genotyping of human papillomavirus using a VeraCode-allele-specific primer extension method.
使用 VeraCode 等位基因特异性引物延伸方法对人乳头瘤病毒进行新型多重基因分型。
DOI:
10.1111/j.1348-0421.2011.00406.x
发表时间:
2012
期刊:
Microbiol Immunol (Wiley-Blackwell)
影响因子:
--
作者:
[Kitamura-Muramatsu Y., Kusumoto-Matsuo R., and Kukimoto I.]
通讯作者:
and Kukimoto I.
Biased amplification of human papillomavirus DNA in specimens containing multiple human papillomavirus types by PCR with consensus primers.
使用共有引物通过 PCR 对含有多种人乳头瘤病毒类型的样本中的人乳头瘤病毒 DNA 进行有偏差的扩增。
DOI:
10.1111/j.1349-7006.2011.01922.x
发表时间:
2011
期刊:
Cancer Sci (Blackwell Publishing)
影响因子:
--
作者:
[Mori S., Nakao S., Kukimoto I., Kusumoto-Matsuo R., Kondo K. and Kanda T]
通讯作者:
Kondo K. and Kanda T
Molecular mechanism of switch in the mode of human papillomavirus DNA replication
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批准号:20890289
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项目类别:Grant-in-Aid for Young Scientists (Start-up)
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资助金额:$2.11万
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财政年份:2008
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负责人:MATSUO Rika
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依托单位:
海外基金