Study of the effects of adrenomedullin upon oral biofilm formation
Study of the effects of adrenomedullin upon oral biofilm formation
批准号:
22592122
负责人:
OZAKI Kazumi
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
在本研究中,我们建立了一株表达和分泌肾上腺髓质素或其相关多肽的重组戈登链霉菌,该菌株是一种具有生物活性和抗菌活性的多肽,并检测了该菌株对牙周病细菌的生长和对口腔链球菌和乳杆菌生物膜形成的抑制作用。
英文摘要
In this study, we developed a recombinant S. gordonii strain expressing and secreting adrenomedullin or its related peptide,which is bioactive and antibacterial peptide, and the ability of the strain to inhibitthe cell growth of periodontopathic bacteria and biofilm formation by oral streptococci and lactobacilli was assayed.
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Oncostatin M synergistically induces CXCL10 and ICAM-1 expression in IL-1beta-stimulated-human gingival fibroblasts.
制瘤素 M 协同诱导 IL-1β 刺激的人牙龈成纤维细胞中 CXCL10 和 ICAM-1 的表达。
DOI:
--
发表时间:
2010
期刊:
Journal of Cellular Biochemistry
影响因子:
4
作者:
[Hosokawa Y, et al.]
通讯作者:
et al.
TLR3 ligandがヒト歯肉線維芽細胞のIL-1β誘導CCL20産生に与える影響
TLR3配体对IL-1β诱导的人牙龈成纤维细胞产生CCL20的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Nihei T , Kunzelmann K-H ,Ohashi K,Hickel R,and Teranaka T, 山崎泰志,小澤寿子,重田優子,他., 細川義隆]
通讯作者:
細川義隆
IL-17A は IL-1βが誘導するヒト歯肉線維芽細胞の CCL20 産生を増強する
IL-17A 增强人牙龈成纤维细胞中 IL-1β 诱导的 CCL20 产生
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[二瓶智太郎, ら, 細川義隆]
通讯作者:
細川義隆
CatechinがTNFSF14刺激ヒト歯肉線維芽細胞のIL-6産生に与える影響
儿茶素对 TNFSF14 刺激的人牙龈成纤维细胞产生 IL-6 的影响
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[細川義隆, 他]
通讯作者:
他
DOI:
10.1016/j.jnutbio.2009.04.005
发表时间:
2010-07-01
期刊:
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
影响因子:
5.6
作者:
[Hosokawa, Yoshitaka, Hosokawa, Ikuko, Matsuo, Takashi]
通讯作者:
Matsuo, Takashi
共 21 条
The future life span of Earth's oxygenated atmosphere
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批准号:20K04066
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2020
-
负责人:OZAKI Kazumi
-
依托单位:
Study of the inhibitory effects of polyphenol loaded titania nanotubes on bacterial growth and biofilm formation
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批准号:19K10132
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
-
财政年份:2019
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负责人:OZAKI Kazumi
-
依托单位:
Proterozoic atmospheric chemistry constrained by an Earth system model of biogeochemistry
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批准号:19K21055
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项目类别:Grant-in-Aid for Research Activity Start-up
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资助金额:$1.91万
-
财政年份:2018
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负责人:OZAKI Kazumi
-
依托单位:
Study of the effects of polyphenol-silver nanoparticles complex upon oral biofilm formation and antimicrobial activity
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批准号:16K11554
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
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财政年份:2016
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负责人:OZAKI Kazumi
-
依托单位:
Study of the effects of serine proteases on the cariogenicity of Streptococcus mutans
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批准号:25462962
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2013
-
负责人:OZAKI Kazumi
-
依托单位:
Study of quorum-sensing system of invading bacteria in dentinal caries
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批准号:19592204
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
-
负责人:OZAKI Kazumi
-
依托单位:
Study on synthesizing of intracellular polysaccharide by Streptococcus mutans in dentinal tubules.
-
批准号:17591993
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2005
-
负责人:OZAKI Kazumi
-
依托单位:
Study on Streptococcus mutans sucrose-dependent adherence and cariogenesis.
-
批准号:15592021
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:2003
-
负责人:OZAKI Kazumi
-
依托单位:
Detection of bacterial species using 16S rDNA existed in deep layers of carious lesions with pulp exposure embedded with plastic material and analysis of the pathogenesis of pulpitis
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批准号:13672000
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2001
-
负责人:OZAKI Kazumi
-
依托单位:
Examination of the histological and bacteriological features of the interface between bacterial deposits and root dentin using a device that included exposed root dentin reproduced pulpal pressure in vitro.
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批准号:11671896
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:1999
-
负责人:OZAKI Kazumi
-
依托单位:
海外基金