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The role of epithelial-mesenchymal transition in metastasis and progression of pediatric solid tumors.

The role of epithelial-mesenchymal transition in metastasis and progression of pediatric solid tumors.
上皮间质转化在儿科实体瘤转移和进展中的作用。
批准号:
22659317
负责人:
KOMURO Hiroaki
金额:
$2.14万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
The epithelial to mesenchymal transition (EMT) is an important mechanism for both the initiation of tumor invasion and subsequent metastasis. We investigated the role of EMT in the progression of Neuroblastoma (NB). Downregulation of KRT19 was highly associated with tumor progression in NB as well as metastasis in localized primary NB. Low expression of ERBB3 was also associated with progression of NB. Expression levels of EMT-related genes might become new promising prognostic markers for neuroblastoma.
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Management of Cervicomediastinal Neuroblastoma Presenting With Life-threatening Tracheal Obstruction in Infancy
婴儿期出现危及生命的气管阻塞的颈纵隔神经母细胞瘤的治疗
DOI: 10.1097/mph.0b013e31827b4747
发表时间: 2013
期刊: Journal of Pediatric Hematology/Oncology
影响因子: --
作者: [H. Komuro, Noriko Hoshino]
通讯作者: Noriko Hoshino
Slow release of basic fibroblast growth factor (b-FGF) promotes growth of tracheal cartilage
碱性成纤维细胞生长因子(b-FGF)缓慢释放促进气管软骨生长
DOI: --
发表时间: 2013
期刊: J Pediatr Surg
影响因子: 2.4
作者: [Ishimaru T, Komura M, Komura H, Otani Y, Komuro H, Sugiyma M, Terawaki K, Suzuki K, Tabata Y, Iwanaka T]
通讯作者: Iwanaka T
Bile duct duplication as a cause of distal bowel gas in neonatal duodenal obstruction.
胆管重复是新生儿十二指肠梗阻远端肠积气的原因。
DOI: 10.1016/j.jpedsurg.2011.09.018
发表时间: 2011
期刊: Journal of Pediatric Surgery
影响因子: 2.4
作者: [Komuro H, Ono K, Hoshino N, Urita Y, Gotoh C, Fujishiro J, Shinkai T3Ikebukuro K]
通讯作者: Shinkai T3Ikebukuro K
DOI: 10.1007/s00247-012-2435-x
发表时间: 2012
期刊: Pediatric Radiology
影响因子: 2.3
作者: [Komuro H, Gotoh C]
通讯作者: Gotoh C
11
    Change in catastrophic eruptions the volcanic processes from the continental margin to the island arc
    • 批准号:
      22540469
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.58万
    • 财政年份:
      2010
    • 负责人:
      KOMURO Hiroaki
    • 依托单位:
    Regenerative medicine for pediatric surgical diseases using stem cells with their improved microenvironments.
    Stem cell research in ordermade regenerative medicine for pediatric patients and application of amniotn
    • 批准号:
      17390472
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $4.81万
    • 财政年份:
      2005
    • 负责人:
      KOMURO Hiroaki
    • 依托单位:
    Gravity Anomaly on the Mashu Caldera
    • 批准号:
      15540435
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $0.83万
    • 财政年份:
      2003
    • 负责人:
      KOMURO Hiroaki
    • 依托单位:
    海外基金