The mechanism of Nup98-fusion mediated oncogenesis.
The mechanism of Nup98-fusion mediated oncogenesis.
批准号:
23570228
负责人:
OKA Masahiro
金额:
$3.49万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
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英文摘要
The function of oncogenic Nup98-fusion protein remains almost unknown. Our study demonstrated that Nup98-Hox localizes as small dots in the nucleus that frequently associated with specific histone modifications. Furthermore, the formation of these nuclear dots was dependent on the FG repeats of Nup98 and its associated factors.
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Nucleocytoplasmic shuttling of estrogen receptor α.
雌激素受体α的核细胞质穿梭。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Moriyama T, 他]
通讯作者:
他
The role of Rael in Nup98-fusion mediated leukemogenesis
Rael 在 Nup98 融合介导的白血病发生中的作用
DOI:
10.4161/cc.10.12.15759
发表时间:
2011
期刊:
Cell Cycle.
影响因子:
--
作者:
[Oka, M., Yoneda, Y.]
通讯作者:
Y.
様々なNup98融合タンパク質の細胞内局在・機能の解析
多种Nup98融合蛋白的细胞内定位和功能分析
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[1. Furuse M, Izumi Y, Oda Y, Higashi T, Iwamoto N., 村苑子,岡正啓,米田悦啓]
通讯作者:
村苑子,岡正啓,米田悦啓
Nup98融合遺伝子による細胞がん化のメカニズム
Nup98融合基因引起细胞癌变的机制
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[岡正啓, 米田悦啓]
通讯作者:
米田悦啓
Comparative Expression/Functional Analysis of Karyopherin-βs in Mouse Embryonic Stem Cells and Differentiated Cells
小鼠胚胎干细胞和分化细胞中核转运蛋白-β的比较表达/功能分析
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Sangel P, Oka M, Yoneda Y.]
通讯作者:
Yoneda Y.
共 12 条
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