Analysis of the potential roles of Nucleoporin in oncogenesis
Analysis of the potential roles of Nucleoporin in oncogenesis
批准号:
20570184
负责人:
OKA Masahiro
金额:
$3.16万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Nup98 is a frequent target of chromosomal rearrangements in leukemia, which is associated with the disease development. Our study revealed that Nup98 binds to Crm1, a nuclear export factor, and is involved in protein export from the nucleus to the cytoplasm. In addition, we demonstrated that the expression of Nup98-HoxA9 fusion inhibits the nuclear export.
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DOI:
10.1091/mbc.e09-12-1041
发表时间:
2010-06-01
期刊:
Molecular biology of the cell
影响因子:
3.3
作者:
[Oka M, Asally M, Yasuda Y, Ogawa Y, Tachibana T, Yoneda Y]
通讯作者:
Yoneda Y
A mobile nucleoporin, Nup98, plays an important role in a Crm1-dependent nuclear export
移动核孔蛋白 Nup98 在 Crm1 依赖性核输出中发挥重要作用
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[岡正啓, 浅利宗弘, 安田善也, 立花太郎, 米田悦啓]
通讯作者:
米田悦啓
DOI:
10.1111/j.1742-4658.2010.07982.x
发表时间:
2011-02-01
期刊:
FEBS JOURNAL
影响因子:
5.4
作者:
[Asally, Munehiro, Yasuda, Yoshinari, Yoneda, Yoshihiro]
通讯作者:
Yoneda, Yoshihiro
The role of Nup98 in a Crm1-mediated nuclear export.
Nup98 在 Crm1 介导的核输出中的作用。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Oka, M., Asally, M., Yasuda, Y., Yoneda, Y.]
通讯作者:
Y.
DOI:
10.1016/j.bbagen.2010.04.004
发表时间:
2010-09-01
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
影响因子:
3
作者:
[Okada, Minoru, Oka, Masahiro, Yoneda, Yoshihiro]
通讯作者:
Yoneda, Yoshihiro
共 18 条
Studies on Crm1 that binds to Hox clusters
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批准号:16K14676
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2016
-
负责人:OKA Masahiro
-
依托单位:
Role of PLC epsilon-PKC myu pathway in skin inflammation, skin cancer, cataract, and psoriasis vulgaris.
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批准号:26461692
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
-
财政年份:2014
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负责人:OKA Masahiro
-
依托单位:
The mechanism of Nup98-fusion mediated oncogenesis.
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批准号:23570228
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.49万
-
财政年份:2011
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负责人:OKA Masahiro
-
依托单位:
Role of phospholipase C epsilon in ultraviolet-induced skin carcinogenesis, skin inflammation, cataract, and psoriasis
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批准号:23591645
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.33万
-
财政年份:2011
-
负责人:OKA Masahiro
-
依托单位:
Role and regulation of STAT3 in constitutive production of IL-8 in malignant melanoma cells
-
批准号:19591305
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
-
负责人:OKA Masahiro
-
依托单位:
Role and regulation of phosphatidylinositol 3-kinase in melanoma cells
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批准号:17591171
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2005
-
负责人:OKA Masahiro
-
依托单位:
Role of β isoform of protein kinase C in hepatocyte growth factor-induced signal transduction in pigment cells
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批准号:15591177
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2003
-
负责人:OKA Masahiro
-
依托单位:
Study of the role of protein kinase C-phosphoipase D signaling pathway in pigment cells.
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批准号:13670886
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2001
-
负责人:OKA Masahiro
-
依托单位:
Analysis of function of protein kinase C isozymes in pigment cells by gene transfection using adenovirus vectors
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批准号:11670830
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:1999
-
负责人:OKA Masahiro
-
依托单位:
海外基金