Change of brain blood flow with BOLD MRI during expired gas contorol

模拟二氧化碳（CO2）的消除和氧气（O2）的吸附是基于我们的CO2和O2在体内的运输模型创建的。研制了安装该模拟器的潮汐末二氧化碳、氧气压力（petco2和o2）自动独立控制系统。将该系统应用于有自主呼吸的受试者，并进行petco2和o2对照试验。由此建立了精确、独立的PETCO2&O2控制方法。我们正在研究自发呼吸受试者在petco2和o2上下阶跃变化期间，BOLD fMRI图像中petco2和o2数据与脑血流量之间的关系。

The simulator for elimination of carbon dioxide (CO2) and adsorption of oxygen (O2) was created, based on our CO2 & O2 transport model in the body. The auto end-tidal carbon dioxide & oxygen pressure (PETCO2&O2) independent control system installing the simulator was developed. The system was applied to subjects with spontaneous breathing and the PETCO2&O2 control tests were performed. In consequence the precise and independent PETCO2&O2 control method was established. We are investigating the relationships between PETCO2&O2 data and brain blood flow from BOLD fMRI image during PETCO2&O2 up & down step change in spontaneous breathing subjects.