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Comprehensive Assessment of Pulmonary Functions Using HyperpolarizedXenon-129 Magnetic Resonance Imaging

Comprehensive Assessment of Pulmonary Functions Using HyperpolarizedXenon-129 Magnetic Resonance Imaging
使用超极化Xenon-129 磁共振成像对肺功能进行综合评估
批准号:
23700534
负责人:
IMAI Hirohiko
金额:
$2.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
To develop a method for evaluating pulmonary diseases noninvasively and comprehensively using hyperpolarized xenon-129 magnetic resonance imaging (HP ^129Xe MRI), we studied on the sensitivity improvement in Xe MRI and the methodology for deriving regional pulmonary functions. As a result, a 3-fold improvement in ^129Xe nuclear spin polarization was achieved using a narrow-band laser diode. Newly-proposed techniques made possible to evaluate regional Xe uptake and ventilation. In the application to a mouse model of COPD, we have demonstrated the utility of these methods for detecting pulmonary dysfunctions.
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海外の最新事情-ISMRM2012から
海外最新消息——来自ISMRM2012
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [今井宏彦, 他 (全 7 名), Hirohiko Imai, 今井宏彦]
通讯作者: 今井宏彦
海外の最新事情-ISMRM2011から
海外最新消息——来自ISMRM2011
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Hirohiko Imai, et al. (全 4 名), Hirohiko Imai, Hideaki Fujiwara, 今井宏彦]
通讯作者: 今井宏彦
Origin of dissolved-phase hyperpolarized 129Xe signal in the mouse chest based on experimental evidence from extensive magnetic resonace measurements
基于广泛磁共振测量的实验证据,小鼠胸部溶解相超极化 129Xe 信号的起源
DOI: --
发表时间: 2011
期刊: Magnetic Resonance in Medical Sciences
影响因子: 3
作者: [Michiko Narazaki, et al., 渡部裕輝, Hirohiko Imai, Yuuki Watanabe and Dai Kamiyama, Michiko Narazaki]
通讯作者: Michiko Narazaki
Simultaneous T1and T2mapping from inversion recovery TrueFISP experiments for the robust assessment of cardiac functions
来自反转恢复 TrueFISP 实验的同步 T1 和 T2 映射,用于对心脏功能进行稳健评估
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Hideaki Fujiwara, 他]
通讯作者:
24
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