Indigenous Trauma & Resilience Research Center

总体项目摘要 土著居民经历着与创伤有关的重大健康差距，包括成瘾、 创伤应激障碍、慢性病、婴儿死亡率和自杀。其中许多差距更大 美国印第安人（AI）在达科塔州人工智能社区还面临着历史和代际问题， 数十年的创伤性损失和被迫同化所造成的创伤。因此，我们将建立土著 UND的创伤与复原力研究中心，以解决未解决的创伤对健康的影响， 文化联系和复原力的保护因素。该中心将由三个相互关联的 研究项目-每个项目由一名早期职业调查员领导，并由资深科学家导师协助。 目的： 1.建立一个国家认可和赞誉的土著创伤和复原力研究中心， 我们的目标是改善AI的健康和福祉。 2.为项目负责人提供支持和指导，以确保未来成功获得R 01资金。 3.建立行政、社区参与和外联以及人类受试者核心， 支持该中心，并将提供服务，以加强研究能力，以解决土著健康。 方法：三个研究项目包括：（1）历史创伤和复原力作为一种生物学状态及其 与传统土著食物chokeberry的影响有关;（2）寄宿学校的影响 参加知觉压力，非稳态负荷和弹性;（3）压力和健康的美国印第安人 怀孕。我们将利用UND的现有资产，包括几个机构发展奖 （IDEA）程序。将提供指导，通过行政核心支持项目领导人 由项目主任/主要研究者（PD/PI）、内部和外部咨询委员会组成， 以及一批高水平的科研项目导师。每个项目负责人都将使用基于社区的， 参与性研究原则，并将完成部落社区参与培训模块， 是由PD/PI开发的社区参与和外展核心将由Melanie博士领导 来自ND的Chippewa印第安人海龟山乐队的Nadeau。人类受试者的文化因素 生物样本的研究和收集将得到人类受试者核心的支持， 在研究合规和处理文化规范方面提供技术援助。重大机遇 存在元奖学金，其中COBRE利益相关者将发布最佳和有前途的实践，以支持 社区参与的人类受试者与土著居民的研究。该中心将是可持续的， 竞争力的许多其他赠款计划，包括研究项目赠款（R 01）和相关资金。

OVERALL PROJECT ABSTRACT Indigenous populations experience significant trauma-related health disparities, including addiction, post- traumatic stress disorder, chronic diseases, infant mortality, and suicide. Many of these disparities are worse for American Indians (AIs) in the Dakotas. AI communities also contend with historical and intergenerational trauma from decades of traumatic losses and forced assimilation. Hence, we will establish the Indigenous Trauma & Resilience Research Center at UND to address the health impact of unresolved trauma and the protective factors of cultural connectedness and resilience. The Center will consist of three interrelated research projects—each led by an early career investigator and assisted by senior scientist mentors. Objectives: 1. Establish a nationally-recognized and acclaimed Indigenous Trauma & Resilience Research Center at UND with a goal to improve AI health and well-being. 2. Provide support and mentoring to the Project Leaders to enable future success in obtaining R01 funding. 3. Establish Administrative, Community Engagement & Outreach, and Human Subjects Cores that will support the Center and will provide services to strengthen research capacity to address Indigenous health. Methods: Three research projects include: (1) Historical trauma and resilience as a biological state and its association with the effects of the traditional Indigenous food chokeberry; (2) Impact of boarding school attendance on perceived stress, allostatic load and resilience; and (3) Stress and health in American Indian pregnancies. We will leverage existing assets at UND, including several Institutional Development Award (IDeA) programs. Mentoring will be provided to support the project leaders through an Administrative Core consisting of the Program Director/Principal Investigator (PD/PI), Internal and External Advisory Committees, and a group of high-level scientific Project Mentors. Each project leader will use community-based, participatory research principles and will complete the Tribal Community Engagement Training Module that was developed by the PD/PI. A Community Engagement & Outreach Core will be led by Dr. Melanie Nadeau of the Turtle Mountain Band of Chippewa Indians from ND. Cultural considerations for human subjects research and collection of biological samples will be supported by a Human Subjects Core that will provide technical assistance regarding research compliance and addressing cultural norms. Significant opportunities exist for meta-scholarship in which COBRE stakeholders will publish best and promising practices to support community-engaged human subjects research with Indigenous populations. The center will be sustainable and competitive for numerous other grant programs, including Research Project Grants (R01) and related funding.