Indigenous Trauma & Resilience Research Center

本土创伤

• 批准号: 10360438
• 负责人: Jonathan David Geiger
• 金额: $ 204.88万
• 依托单位: UNIVERSITY OF NORTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10360438
• 关键词: Address; Advisory Committees; Age; American Indians; Assimilations; Award; Basic Science; Behavioral; Biological; Centers of Research Excellence; Cessation of life; Chippewa; Chronic Disease; Collection; Communities; Community Outreach; Core Grant; Development; Enrollment; Ensure; Epigenetic Process; Faculty; Food; Funding; Funding Opportunities; Future; Goals; Grant; Health; Health Promotion; Human Subject Research; Indigenous; Individual; Infant Mortality; Interdisciplinary Study; Link; Mentors; Methods; Monoclonal Antibody R24; Native-Born; North Dakota; Outcome; Peer Review; Personal Satisfaction; Population; Post-Traumatic Stress Disorders; Poverty; Pregnancy; Principal Investigator; Publishing; Research; Research Assistant; Research Infrastructure; Research Personnel; Research Project Grants; Risk Factors; Sampling; Scholarship; Schools; Senior Scientist; Services; Social Conditions; Stress; Suicide; Teton Sioux Indian; Training; Training Activity; Translational Research; Trauma; Tribes; Turtles; Unemployment; United States National Institutes of Health; Universities; Work; academic program; addiction; allostatic load; base; career; community based participatory research; community engagement; emotional trauma; experience; faculty research; graduate student; health disparity; health inequalities; human subject; improved; indigenous community; infrastructure development; interest; intergenerational; member; perceived stress; programs; protective factors; psychological trauma; ranpirnase; resilience; skills; success; tribal community

OVERALL PROJECT ABSTRACT Indigenous populations experience significant trauma-related health disparities, including addiction, post- traumatic stress disorder, chronic diseases, infant mortality, and suicide. Many of these disparities are worse for American Indians (AIs) in the Dakotas. AI communities also contend with historical and intergenerational trauma from decades of traumatic losses and forced assimilation. Hence, we will establish the Indigenous Trauma & Resilience Research Center at UND to address the health impact of unresolved trauma and the protective factors of cultural connectedness and resilience. The Center will consist of three interrelated research projects—each led by an early career investigator and assisted by senior scientist mentors. Objectives: 1. Establish a nationally-recognized and acclaimed Indigenous Trauma & Resilience Research Center at UND with a goal to improve AI health and well-being. 2. Provide support and mentoring to the Project Leaders to enable future success in obtaining R01 funding. 3. Establish Administrative, Community Engagement & Outreach, and Human Subjects Cores that will support the Center and will provide services to strengthen research capacity to address Indigenous health. Methods: Three research projects include: (1) Historical trauma and resilience as a biological state and its association with the effects of the traditional Indigenous food chokeberry; (2) Impact of boarding school attendance on perceived stress, allostatic load and resilience; and (3) Stress and health in American Indian pregnancies. We will leverage existing assets at UND, including several Institutional Development Award (IDeA) programs. Mentoring will be provided to support the project leaders through an Administrative Core consisting of the Program Director/Principal Investigator (PD/PI), Internal and External Advisory Committees, and a group of high-level scientific Project Mentors. Each project leader will use community-based, participatory research principles and will complete the Tribal Community Engagement Training Module that was developed by the PD/PI. A Community Engagement & Outreach Core will be led by Dr. Melanie Nadeau of the Turtle Mountain Band of Chippewa Indians from ND. Cultural considerations for human subjects research and collection of biological samples will be supported by a Human Subjects Core that will provide technical assistance regarding research compliance and addressing cultural norms. Significant opportunities exist for meta-scholarship in which COBRE stakeholders will publish best and promising practices to support community-engaged human subjects research with Indigenous populations. The center will be sustainable and competitive for numerous other grant programs, including Research Project Grants (R01) and related funding.

总体项目摘要 土著居民经历着与创伤相关的重大健康差异，包括成瘾、创伤后应激障碍 创伤性应激障碍、慢性疾病、婴儿死亡率和自杀。其中许多差异更加严重 达科他州的美洲印第安人 (AI)。人工智能社区还应对历史和代际问题 数十年的创伤性损失和被迫同化造成的创伤。因此，我们将建立原住民 UND 创伤与复原力研究中心致力于解决未解决的创伤对健康的影响以及 文化联系和复原力的保护因素。该中心将由三个相互关联的 研究项目——每个项目均由早期职业研究者领导，并由资深科学家导师协助。 目标： 1. 在以下地点建立一个全国认可且广受赞誉的土著创伤和复原力研究中心 UND 的目标是改善人工智能的健康和福祉。 2. 为项目负责人提供支持和指导，以确保未来成功获得 R01 资金。 3. 建立行政、社区参与和外展以及人类受试者核心， 支持该中心并将提供服务以加强解决土著健康问题的研究能力。 方法：三个研究项目包括：（1）历史创伤和复原力作为一种生物状态及其 与传统土著食物苦莓的影响有关； (2)寄宿学校的影响 关注感知压力、静态负荷和恢复力； (3) 美洲印第安人的压力与健康 怀孕。我们将利用 UND 的现有资产，包括多项机构发展奖 （IDeA）程序。将通过行政核心提供指导以支持项目领导者 由项目总监/首席研究员 (PD/PI)、内部和外部咨询委员会组成， 以及一批高水平的科研项目导师。每个项目负责人都将使用基于社区的、 参与性研究原则，并将完成部落社区参与培训模块 由 PD/PI 开发。社区参与和外展核心将由 Melanie 博士领导 来自北达科他州的奇珀瓦印第安人龟山乐队的纳多。对人类受试者的文化考虑 生物样本的研究和收集将得到人类受试者核心的支持，该核心将提供 有关研究合规性和解决文化规范的技术援助。重大机遇 元奖学金的存在，其中 COBRE 利益相关者将发布最佳和有前途的实践来支持 社区参与的人类受试者研究与土著居民。该中心将是可持续的并且 与许多其他资助计划相比具有竞争力，包括研究项目资助 (R01) 和相关资金。