Frontiers in Addiction Research and Pregnancy

成瘾研究和怀孕的前沿

• 批准号: 10359163
• 负责人: GERALD SCHATTEN
• 金额: $ 36.15万
• 依托单位: MAGEE-WOMEN'S RES INST AND FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-04-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10359163
• 关键词: Address; Adopted; Affect; African American population; Alcohol abuse; Animals; Attention; Behavioral Research; Biomedical Research; Birth; Child; Clinical; Clinical Research; Collaborations; Color; Communities; Development Plans; Doctor of Philosophy; Education; Educational workshop; Elderly; Ensure; Environmental Risk Factor; Evaluation; Faculty; Family; Fostering; Funding; Future; Goals; Grant; Growth; Health Professional; Hispanic Americans; Hispanic-serving Institution; Historically Black Colleges and Universities; Individual; Institution; Instruction; Investments; Laboratories; Laboratory Research; Learning; Mainstreaming; Medical; Medical Students; Mentors; Methods; Minority-Serving Institution; Modeling; Morehouse School of Medicine; National Institute of Drug Abuse; Neonatal Abstinence Syndrome; Outcome; Participant; Pediatrics; Pharmaceutical Preparations; Physicians; Postdoctoral Fellow; Pregnancy; Pregnant Women; Psychologist; Publishing; Quantitative Evaluations; Recommendation; Reproducibility; Research; Research Personnel; Research Training; Resources; Scientist; Self Administration; Series; Sexually Transmitted Diseases; Study Section; Substance abuse problem; Training; Training and Education; Underrepresented Minority; United States National Institutes of Health; Universities; Vulnerable Populations; Woman; Women' s Health; addiction; base; career; career development; cost effective; design; drug withdrawal; education research; ethical legal social implication; frontier; graduate student; health disparity; human subject; improved; innovation; lectures; member; minority communities; minority scientist; minority trainee; neonate; peer; people of color; pregnant; programs; recruit; responsible research conduct; skill acquisition; skills; teaching assistant; tobacco abuse; tool; translational approach

PROGRAM SUMMARY/ABSTRACT This revised application entitled `Frontiers in Addiction Research and Pregnancy [FrARP]' requests R25 funding within NIDA's Research Education Program, responsive to PAR-16-224. FrARP recruits, educates and helps launch the careers of clinical researchers and clinicians, primarily under-represented minorities (URMs), starting with an advanced lab course for skills development followed with mentored research, career mentoring, tracking and evaluations. The course has formal and individual career development components ensuring that each participant is well versed in vital skills for designing, conducting, and publishing independent research, obtaining grants, and launching and sustaining independent careers. The target audience is graduate and medical students, postdoctoral fellows, and early stage scientists and clinicians. The courses are offered exclusively at URM institutions: Morehouse School of Medicine (a historically Black Institution) in 2018, 2020, and 2022, and San Diego State University (a Hispanic Serving Institution) in 2019 and 2021. In addition to recruiting URM scientists, FrARP concentrates on a uniquely vulnerable population— pregnant women who abuse substances and their babies with neonatal abstinence syndrome. These medical challenges are serious, growing issues for families and for our Nation. Justifications include: the growth of addiction research; clinical challenges resulting from addiction during pregnancy; and the paucity of labs led by URM scientists. FrARP's Executive Committee includes Program Director Gerald Schatten, PhD, at Pitt and Co-PD Michael Kuhar, PhD, at Emory (Addiction Research Leader), together with Co-Is Steve Caritis, MD, at Pitt (Addiction Obstetrician), Thereasa Cronan, PhD, at SDSU (Facilitator, Psychologist, URM and Women's Health), Calvin Simerly, PhD, at Pitt (Course Implementer), Evan Snyder, MD, PhD, at SBP (Addiction Neonatologist), and Winston Thompson, PhD, at MSM (Facilitator, URM and Women's Health). It is overseen by a Scientific Advisory Board. Related courses have been successful in attracting URMs (31% African- Americans; 29% Hispanic Americans; 65% women; 51% from URM institutions). Five Specific Aims are proposed. I. FrARP Advanced Lab Course for skills development provides conceptual education and research training; II. Mentored Addiction Research; III. Career Planning Tools; IV. Responsible Research Conduct; and V. Unbiased Quantitative Evaluations to ensure that this R25 is a wise, cost-effective investment. The R25's goals, then, are to provide courses in skills development, mentored addiction research, and ongoing career support resulting in comprehensive, sophisticated training in clinical and translational strategies for addressing the current challenges in addiction during pregnancy, for designing better therapies for the future, and for launching and sustaining successful careers in substance abuse, pregnancy, pediatrics and related fields. In so doing, FrARP will help to advance the careers of the most promising clinical scientists and clinicians, with sensitivity for ensuring full diversity in the NIDA workforce.

项目概要/摘要 这份题为“成瘾研究和怀孕前沿 [FrARP]”的修订申请要求 R25 NIDA 研究教育计划内的资金，响应 PAR-16-224。 FrARP 招募、教育和 帮助临床研究人员和临床医生（主要是代表性不足的少数群体（URM））开启职业生涯， 从技能发展的高级实验室课程开始，然后是指导研究、职业生涯 指导、跟踪和评估。该课程包含正式和个人职业发展部分 确保每个参与者都精通设计、指挥和出版的重要技能 独立研究、获得资助以及开展和维持独立职业生涯。目标 观众是研究生和医学生、博士后研究员以及早期科学家和临床医生。这 课程仅在 URM 机构提供： 莫尔豪斯医学院（历史悠久的黑人医学院） 机构）（2018 年、2020 年和 2022 年）以及圣地亚哥州立大学（西班牙裔服务机构）2019 年 2021 年。除了招募 URM 科学家外，FrARP 还重点关注独特的弱势群体—— 滥用药物的孕妇及其患有新生儿戒断综合症的婴儿。这些医疗 对于家庭和我们的国家来说，挑战是严峻且日益严重的问题。理由包括： 成瘾研究；怀孕期间成瘾带来的临床挑战；以及由以下人员领导的实验室的缺乏 URM 科学家。 FrARP 的执行委员会包括匹兹堡大学的项目总监 Gerald Schatten 博士和 埃默里大学的联合PD Michael Kuhar博士（成瘾研究负责人），以及埃默里大学的联合PD Steve Caritis医学博士 Pitt（成瘾产科医生）、Thereasa Cronan 博士，SDSU（协调员、心理学家、URM 和妇女 健康）、Pitt 的 Calvin Simerly 博士（课程实施者）、SBP 的 Evan Snyder 医学博士、博士（成瘾） 新生儿学家）和 MSM 的 Winston Thompson 博士（URM 和妇女健康协调员）。是受监督的 由科学顾问委员会。相关课程已成功吸引 URM（31% 非洲裔） 美国人； 29% 西班牙裔美国人； 65% 为女性； 51% 来自 URM 机构）。五个具体目标是 建议的。 I. FrARP 技能发展高级实验室课程提供概念教育和 研究培训；二.指导成瘾研究；三．职业规划工具；四．负责任的研究 执行; V. 公正的定量评估，以确保这款 R25 是明智的、具有成本效益的 投资。 R25 的目标是提供技能开发课程、指导成瘾研究、 以及持续的职业支持，从而提供全面、复杂的临床和转化培训 解决当前怀孕期间成瘾挑战的策略，设计更好的疗法 为了未来，为了在药物滥用、怀孕、儿科领域开展和维持成功的职业生涯 及相关领域。通过这样做，FrARP 将帮助推动最有前途的临床科学家的职业生涯 和临床医生，具有确保 NIDA 员工队伍充分多样性的敏感性。