Frontiers in Addiction Research and Pregnancy

数据摘要/摘要 这份题为"成瘾研究和怀孕前沿"的修订申请要求R25 NIDA的研究教育计划内的资金，响应PAR-16 - 224。FrARP招募，教育和 帮助启动临床研究人员和临床医生的职业生涯，主要是代表性不足的少数民族（URM）， 首先是技能发展的高级实验室课程，然后是指导研究，职业生涯 指导、跟踪和评估。该课程有正式的和个人的职业发展部分 确保每个参与者都精通设计，指挥和出版的重要技能 独立研究，获得赠款，启动和维持独立的职业生涯。目标 观众是研究生和医学生，博士后研究员和早期科学家和临床医生。的 课程只在URM机构提供：莫尔豪斯医学院（历史上的黑人 机构）在2018年，2020年和2022年，圣地亚哥州立大学（西班牙裔服务机构）在2019年 和2021年。除了招募URM科学家，FrARP还专注于一个独特的弱势群体- 滥用药物的孕妇及其患有新生儿戒断综合症的婴儿。这些医疗 挑战是严重的，对家庭和我们的国家来说，问题越来越大。理由包括： 成瘾研究;怀孕期间成瘾导致的临床挑战;以及缺乏由 URM科学家。FrARP的执行委员会包括项目主任杰拉尔德Schatten，博士，在皮特和 埃默里大学的共同PD Michael Kuhar博士（成瘾研究负责人），以及共同Is Steve Caritis医学博士， 皮特（成瘾产科医生），Theresa Cronan，博士，在SDSU（调解人，心理学家，URM和妇女的 健康），卡尔文Simerly，博士，在皮特（课程实施），埃文斯奈德，医学博士，博士，在SBP（成瘾 新生儿科医生）和温斯顿汤普森，博士，在男男性接触者（主持人，URM和妇女健康）。它被监督 一个科学顾问委员会。相关课程成功地吸引了统一登记册管理单位（31%为非洲国家， 美国人; 29%西班牙裔美国人; 65%女性; 51%来自URM机构）。五个具体目标是 提出了I. FrARP高级技能发展实验室课程提供概念教育， 研究训练;二。成瘾研究;三。职业规划工具;四。负责任的研究 进行;和五.无偏见的定量评估，以确保这一R25是一个明智的，具有成本效益的 投资因此，R25的目标是提供技能发展课程，指导成瘾研究， 以及持续的职业支持，从而在临床和翻译方面提供全面，复杂的培训 应对当前怀孕期间成瘾挑战的战略，设计更好的治疗方法 为了未来，为了在药物滥用、怀孕、儿科等领域开展和维持成功的职业生涯， 和相关领域。通过这样做，FrARP将有助于推动最有前途的临床科学家的职业生涯 和临床医生，具有确保NIDA劳动力充分多样性的敏感性。

PROGRAM SUMMARY/ABSTRACT This revised application entitled `Frontiers in Addiction Research and Pregnancy [FrARP]' requests R25 funding within NIDA's Research Education Program, responsive to PAR-16-224. FrARP recruits, educates and helps launch the careers of clinical researchers and clinicians, primarily under-represented minorities (URMs), starting with an advanced lab course for skills development followed with mentored research, career mentoring, tracking and evaluations. The course has formal and individual career development components ensuring that each participant is well versed in vital skills for designing, conducting, and publishing independent research, obtaining grants, and launching and sustaining independent careers. The target audience is graduate and medical students, postdoctoral fellows, and early stage scientists and clinicians. The courses are offered exclusively at URM institutions: Morehouse School of Medicine (a historically Black Institution) in 2018, 2020, and 2022, and San Diego State University (a Hispanic Serving Institution) in 2019 and 2021. In addition to recruiting URM scientists, FrARP concentrates on a uniquely vulnerable population— pregnant women who abuse substances and their babies with neonatal abstinence syndrome. These medical challenges are serious, growing issues for families and for our Nation. Justifications include: the growth of addiction research; clinical challenges resulting from addiction during pregnancy; and the paucity of labs led by URM scientists. FrARP's Executive Committee includes Program Director Gerald Schatten, PhD, at Pitt and Co-PD Michael Kuhar, PhD, at Emory (Addiction Research Leader), together with Co-Is Steve Caritis, MD, at Pitt (Addiction Obstetrician), Thereasa Cronan, PhD, at SDSU (Facilitator, Psychologist, URM and Women's Health), Calvin Simerly, PhD, at Pitt (Course Implementer), Evan Snyder, MD, PhD, at SBP (Addiction Neonatologist), and Winston Thompson, PhD, at MSM (Facilitator, URM and Women's Health). It is overseen by a Scientific Advisory Board. Related courses have been successful in attracting URMs (31% African- Americans; 29% Hispanic Americans; 65% women; 51% from URM institutions). Five Specific Aims are proposed. I. FrARP Advanced Lab Course for skills development provides conceptual education and research training; II. Mentored Addiction Research; III. Career Planning Tools; IV. Responsible Research Conduct; and V. Unbiased Quantitative Evaluations to ensure that this R25 is a wise, cost-effective investment. The R25's goals, then, are to provide courses in skills development, mentored addiction research, and ongoing career support resulting in comprehensive, sophisticated training in clinical and translational strategies for addressing the current challenges in addiction during pregnancy, for designing better therapies for the future, and for launching and sustaining successful careers in substance abuse, pregnancy, pediatrics and related fields. In so doing, FrARP will help to advance the careers of the most promising clinical scientists and clinicians, with sensitivity for ensuring full diversity in the NIDA workforce.