Frontiers in Addiction Research and Pregnancy

节目摘要/摘要 这份题为《成瘾研究和怀孕的前沿》的修订申请请求R25 NIDA研究教育计划内的资金，响应PAR-16-224。FARP招募、教育和 帮助启动临床研究人员和临床医生的职业生涯，主要是代表不足的少数族裔(URM)， 首先是针对技能发展的高级实验室课程，然后是指导研究、职业生涯 指导、跟踪和评估。该课程包括正式的和个人的职业发展部分 确保每个参与者都精通设计、执行和出版的重要技能 独立研究、获得资助、启动和维持独立事业。目标是 受众是研究生和医学生、博士后研究员、早期科学家和临床医生。这个 课程只在URM机构提供：莫尔豪斯医学院(历史上的黑人 2018年、2020年和2022年，圣地亚哥州立大学(一所西班牙裔服务机构)于2019年 和2021年。除了招募URM科学家外，FrARP还专注于一个独特的脆弱群体- 滥用药物的孕妇及其新生儿禁欲综合征婴儿。这些医疗人员 对于家庭和我们的国家来说，挑战是严重的、日益严重的问题。理由包括： 成瘾研究；孕期成瘾造成的临床挑战；以及缺乏由以下人员领导的实验室 嗯，科学家们。FrARP的执行委员会包括PIT的项目主任Gerald Schatten博士和 Emory(成瘾研究领导者)的共同PD Michael Kuhar博士和共同研究人员Steve Caritis，医学博士，在 皮特(成瘾产科医生)，Thereasa Cronan博士，SDSU(促进者、心理学家、URM和妇女 健康)，Calvin Simerly，PIT(课程实施者)博士，Evan Snyder，医学博士，SBP(成瘾) 新生儿学家)和MSM(促进者、URM和妇女健康)的温斯顿·汤普森博士。它是受监督的 由一个科学顾问委员会。相关课程成功吸引了URM(31%的非洲人-- 美国人；29%的西班牙裔美国人；65%的女性；51%的人来自URM机构)。五个具体目标是 建议。I.FrARP技能发展高级实验室课程提供概念教育和 研究性培训；II.有指导的成瘾研究；III.职业规划工具；IV.负责任的研究 进行；以及V.不偏不倚的量化评估，以确保这款R25是一款明智的、具有成本效益的 投资。那么，R25的S的目标是提供技能发展、成瘾研究指导课程， 和持续的职业支持，带来全面、复杂的临床和翻译培训 应对目前孕期成瘾挑战的战略，设计更好的治疗方法 为了未来，为了在药物滥用、怀孕、儿科等领域开创和维持成功的职业生涯 以及相关的字段。这样，FrARP将有助于推动最有前途的临床科学家的职业生涯 和临床医生，并敏锐地确保NIDA工作人员的完全多样性。

PROGRAM SUMMARY/ABSTRACT This revised application entitled `Frontiers in Addiction Research and Pregnancy [FrARP]' requests R25 funding within NIDA's Research Education Program, responsive to PAR-16-224. FrARP recruits, educates and helps launch the careers of clinical researchers and clinicians, primarily under-represented minorities (URMs), starting with an advanced lab course for skills development followed with mentored research, career mentoring, tracking and evaluations. The course has formal and individual career development components ensuring that each participant is well versed in vital skills for designing, conducting, and publishing independent research, obtaining grants, and launching and sustaining independent careers. The target audience is graduate and medical students, postdoctoral fellows, and early stage scientists and clinicians. The courses are offered exclusively at URM institutions: Morehouse School of Medicine (a historically Black Institution) in 2018, 2020, and 2022, and San Diego State University (a Hispanic Serving Institution) in 2019 and 2021. In addition to recruiting URM scientists, FrARP concentrates on a uniquely vulnerable population— pregnant women who abuse substances and their babies with neonatal abstinence syndrome. These medical challenges are serious, growing issues for families and for our Nation. Justifications include: the growth of addiction research; clinical challenges resulting from addiction during pregnancy; and the paucity of labs led by URM scientists. FrARP's Executive Committee includes Program Director Gerald Schatten, PhD, at Pitt and Co-PD Michael Kuhar, PhD, at Emory (Addiction Research Leader), together with Co-Is Steve Caritis, MD, at Pitt (Addiction Obstetrician), Thereasa Cronan, PhD, at SDSU (Facilitator, Psychologist, URM and Women's Health), Calvin Simerly, PhD, at Pitt (Course Implementer), Evan Snyder, MD, PhD, at SBP (Addiction Neonatologist), and Winston Thompson, PhD, at MSM (Facilitator, URM and Women's Health). It is overseen by a Scientific Advisory Board. Related courses have been successful in attracting URMs (31% African- Americans; 29% Hispanic Americans; 65% women; 51% from URM institutions). Five Specific Aims are proposed. I. FrARP Advanced Lab Course for skills development provides conceptual education and research training; II. Mentored Addiction Research; III. Career Planning Tools; IV. Responsible Research Conduct; and V. Unbiased Quantitative Evaluations to ensure that this R25 is a wise, cost-effective investment. The R25's goals, then, are to provide courses in skills development, mentored addiction research, and ongoing career support resulting in comprehensive, sophisticated training in clinical and translational strategies for addressing the current challenges in addiction during pregnancy, for designing better therapies for the future, and for launching and sustaining successful careers in substance abuse, pregnancy, pediatrics and related fields. In so doing, FrARP will help to advance the careers of the most promising clinical scientists and clinicians, with sensitivity for ensuring full diversity in the NIDA workforce.