Promoting Diversity in the UNM METALS SRC through Risk-Reduction Research on Tribal Lands

通过部落土地风险降低研究促进 UNM METALS SRC 的多样性

• 批准号: 10395130
• 负责人: Johnnye L Lewis
• 金额: $ 5万
• 依托单位: UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-15 至 2022-09-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10395130
• 关键词: Affect; Area; Basic Science; Chemistry; Collaborations; Communities; Complement; Development; Ecology; Funding Opportunities; Goals; Health; Immobilization; Lead; Master of Science; Mentors; Metal exposure; Metals; Microscopy; Mining; Motivation; Navajo; New Mexico; Oxidation-Reduction; Phase; Plants; Poaceae; Pueblo Race; Research; Research Personnel; Resources; Risk Reduction; Role; Signal Recognition Particle; Site; Spectrum Analysis; Students; Superfund; Symbiosis; Training; Translations; Universities; Work; aqueous; career development; community engaged research; community engagement; experimental study; fungus; graduate student; metal poisoning; novel strategies; plant fungi; remediation; tool; toxic metal; tribal lands; undergraduate student; uptake

Project Summary The goal of this SRP Research Supplement to Promote Diversity in Health-Related Research is to complement efforts for Phase 1 of the University of New Mexico’s Metals Exposure and Toxicity Assessment on Tribal Lands in the Southwest (UNM METALS) Superfund Basic Research Center (SRC) Environmental Project 1 (EP1). The focus of EP1 is on immobilization of metal mixtures for risk reduction in sites affected by mining legacy in our partner communities on Navajo Nation and the Pueblo of Laguna. The motivation of this supplement is to support Taylor Busch, a graduate student of Navajo descent who will synergize the current research in EP1 (focused on metal immobilization of metal mixtures), to explore new approaches that use plant-fungi symbiosis for the remediation of toxic metal mixtures. Taylor Busch will investigate the role of fungi on the accumulation of U and As in plants. We will build from initial work conducted by Taylor Busch who has collaborated with our Center as an undergraduate researcher, using the native grass, Bouteloua gracilis (blue grama) and fungi that have already been isolated from the contaminated areas in our partner community of Laguna Pueblo. We will conduct culture experiments to evaluate uptake of U and As integrating aqueous chemistry, microscopy, and spectroscopy tools for elemental composition and metal speciation in fungi and plants. Taylor Busch will be mentored by Dr. José Cerrato, who is the lead investigator for EP1 and has a strong track-record with under-represented students. Eliane El Hayek will serve as a Co-mentor and will facilitate the integration with biomedical and environmental projects of the UNM METALS SRC. The collaboration with Jennifer Rudgers who is an expert in fungi ecology will be an invaluable asset to this supplement given that Taylor Busch has already been working with her as an undergraduate researcher. The Administrative Core, Translation Core, Training Core and Community Engagement Core will support the mentoring of Taylor Busch and provide invaluable opportunities for professional development working with our partner communities. The proposed activities for this supplement can be feasibly completed by March 31, 2022 which is the end date of Phase of the UNM METALS SRC. We will look for other funding opportunities for Taylor Busch to continue working on this project beyond the end of Phase 1 of the UNM METALS SRC so Taylor Busch can obtain her Master of Science (MS) degree.

项目摘要 本次SRP研究的目标 补充 促进健康相关领域的多样性 研究是为了补充新墨西哥州大学金属项目第一阶段的工作。 西南部部落土地的暴露和毒性评估（UNM金属） 超级基金基础研究中心环境项目1（EP 1）。EP 1的重点是 关于固定金属混合物以减少我国受采矿遗留问题影响的场址的风险的 纳瓦霍民族和拉古纳的普韦布洛的伙伴社区。这样做的动机 补充是支持泰勒布施，纳瓦霍血统的研究生谁将协同 目前的研究在EP 1（侧重于金属混合物的金属固定化），探索新的 利用植物-真菌共生修复有毒金属混合物的方法。泰勒 布施将研究真菌对植物中U和As积累的作用。我们将建立 泰勒·布施（Taylor Busch）与我们中心合作， 本科生研究员，使用本地草，Bouteloua gracilis（蓝色格兰玛）和真菌 已经从我们的合作伙伴社区的污染地区隔离出来， 拉古纳普韦布洛。我们将进行培养实验，以评估U和As的吸收， 元素组成和金属的水化学、显微镜和光谱学工具 真菌和植物中的物种形成。 Taylor Busch将接受EP 1首席研究员José Cerrato博士的指导 在代表性不足的学生中有着良好的记录。Eliane El Hayek将担任 共同指导，并将促进与生物医学和环境项目的整合， UNM METALS SRC.与真菌生态学专家Jennifer Rudgers的合作 将是一个宝贵的资产，这补充考虑到泰勒布施已经在工作， 作为一名本科研究员。管理核心、翻译核心、培训 核心和社区参与核心将支持泰勒布施的指导，并提供 与我们的合作伙伴社区一起工作的宝贵专业发展机会。 该补充的拟议活动可在2022年3月31日之前完成， 是UNM METALS SRC阶段的结束日期。我们将寻找其他融资机会 Taylor Busch在UNM第一阶段结束后继续从事该项目 金属SRC，使泰勒布施可以获得她的理学硕士（MS）学位。