Supporting Multidisciplinary Achievement in Respiratory Research Training (SMARRT)

摘要 该提案旨在解决以下领域对医生和科学家研究人员的关键劳动力需求： 呼吸系统相关疾病。为了培养这样的调查员，我们寻求对教育课程的支持 旨在满足新兴的、有才华的肺、过敏或重症监护的特殊研究培训需求 医学博士后博士生和医学博士研究员。该计划将包括高标准的研究， 跨越整个范围，包括基础发现科学，早期转化研究，临床 调查，人口科学研究和转化研究，从而推动基础 在现实世界中的临床和公共卫生实践的发现。我们的目标是确保成功， 提出一个创新的计划，既包含基本的核心要素，又适应个人 每个学员的需求。我们的计划建立在：1-从我们自己的经验教训，在运行一个 成功的KL 2计划，在早期将学者过渡到独立学术生涯的比率很高， 阶段，2-一个非常成功的创新研究型医学院计划，3-强肺， 过敏和重症监护医学博士奖学金计划和强大的博士博士课程，提供了一个大的游泳池 合格申请人的数量，以及4-已发表的国家导师研究中经过验证的策略， 这些研究报告建议的吸引和留住有前途的年轻人的办法， 在研究中代表性不足的少数群体。我们的T32计划有以下目标：目标1：提供 从事肺、过敏或重症医学的博士后（MD、PhD、MD/PhD）学员， 研究与多学科教学培训，再加上一个团队指导的研究经验。目标2： 通过制定一个培训计划，提高受训人员作为综合多学科团队的一部分工作的能力。 知识基础和研究方法的技能，沟通技巧，专业精神，道德行为， 研究和对可重复发现的严格分析。目标3：征聘、留住和加快 * 培养一批具备多学科技能的年轻调查员， 在基础，临床，转化或人口健康研究的独立研究生涯。一旦他们 完成我们高度适应性的课程，学员将拥有追求卓越的知识和技能 尖端的研究事业，并将能够认识到不同的研究范式的重要性， 从分子医学到公共卫生科学，迅速将科学发现转化为 更好的诊断和治疗。T32提案将填补我们现有研究培训的重要空白 通过提供结构化的研究培训组合。我们预计，该计划支持的学员将 从事实验方法，形成导师-学员关系，并获得额外的研究 经验需要提高竞争力的独立研究和职业发展奖。

ABSTRACT This proposal is designed to address the critical workforce need for physician and scientist investigators in respiratory related disorders. To develop such investigators, we seek support for an educational curriculum designed to meet the special research training needs of emerging, talented pulmonary, allergy, or critical care medicine postdoctoral PhD trainees and MD fellows. The program will include high standards of research that span the entire spectrum comprising fundamental discovery science, early translational research, clinical investigations, population science research, and translational research, thereby moving fundamental discoveries into clinical and public health practice in real-world settings. We aim to ensure success by proposing an innovative program that contains both fundamental core elements yet adapts to the individual needs of each trainee. Our program builds on: 1- Lessons learned from our own experience in running a successful KL2 program with a high rate of transitioning scholars to independent academic careers at an early stage, 2- A highly successful innovative research-oriented medical school program, 3- Strong pulmonary, allergy, and critical care MD fellowship programs and strong PhD doctoral programs which provide a large pool of qualified applicants, and 4- Proven strategies from published national studies on mentorship and approaches recommended by these studies to attract and retain promising young people, especially underrepresented minorities, in research. Our T32 Program has the following AIMS: Aim 1: To provide postdoctoral (MD, PhD, MD/PhD) trainees who are engaged in pulmonary, allergy or critical care medicine and research with multidisciplinary didactic training, coupled to a team mentored research experience. Aim 2: To enhance the ability of trainees to work as part of an integrated, multidisciplinary team by developing a knowledge base and skills in research methods, communication skills, professionalism, the ethical conduct of research and rigorous analysis of reproducible findings. Aim 3: To recruit, retain and accelerate the independent career development of a pool of young investigators with the multidisciplinary skills necessary for an independent research career in basic, clinical, translational or population health research. Once they complete our highly adaptive program, trainees will have the knowledge and skills to pursue outstanding cutting-edge research careers and will be able to recognize the importance of different research paradigms, ranging from molecular medicine to public health sciences, for rapidly translating scientific discoveries into better diagnostics and therapeutics. This T32 proposal will fill an important gap in our existing research training portfolio by providing structured research training. We anticipate that trainees supported by this program will be engaged in experimental approaches, form mentor-trainee relationships and gain the additional research experience needed to enhance competitiveness for independent research and career development awards.