Infectious Diseases Across Scales Training Program

项目摘要 传染病仍然是人类痛苦和死亡的主要原因。虽然许多研究和 培训的重点是研究单一规模的传染病（例如宿主内或人口一级）， 控制传染病的一个主要挑战是，这些疾病通常是跨规模发生的。具体地说， 宿主免疫分子和病原体之间的相互作用决定了它们在人群中的传播 这反过来又决定了疾病在各区域的传播;此外，新出现的疾病的一个主要特点是， 传染病的一个重要特征是它们感染各种各样的非人类宿主，使它们的控制变得复杂。 因此，为了有效地了解和控制传染病，研究人员需要综合 跨学科，跨规模的方法，跨越生物组织的全方位培训，从 分子到生态系统。建议的传染病跨规模培训计划（IDASTP）， 埃默里大学旨在提供这种跨学科的培训。该项目将与30名教师合作 来自多个学校和部门，每年共培养4名研究生，每个学生 获得两年的培训。学生将从总共约19名符合培训条件的学生中招募， 在与免疫学、人口相关的传染病研究方面具有卓越优势的研究生课程 生物学和公共卫生。在这些方案中，培训的最重要组成部分是研究，首先是作为一部分， 实验室的轮换，然后作为论文项目的一部分。IDASTP学员将获得以下综合培训： 通过跨学科课程和整合研究和 控制各种规模的传染病。他们还将参加一个双周传染病论坛 以及由本地及外地传染病专家主讲的传染病周年研讨会。 研讨会和专题讨论会将集中在跨尺度相互作用，控制应用和 职业发展，提供研讨会，让学生接触跨学科的职业机会， 学术和非学术环境。跨规模的学生培训的进一步整合是由 成立论文委员会，其中包括在不同的传染病研究的专业知识的教师 鳞片该培训计划的总体目标是培养受过广泛培训和有竞争力的科学家， 使用跨学科和跨规模的方法来更好地研究和控制传染病。毕业生 该计划将获得：跨尺度疾病动力学的广泛知识;深入了解他们的 研究领域;有效开发研究项目，赠款提案，演示文稿和 出版物;以及对传染病博士的职业轨迹的赞赏。的 在埃默里大学实施这一计划将吸引和留住一流的学生，并产生新的 能够利用跨学科工具集有效应对传染病的专家群体。

Project Summary Infectious diseases continue to be a major cause of human suffering and mortality. While much research and training has focused on studying infectious disease at a single scale (e.g. within hosts or at the population level), a major challenge in the control of infectious diseases is that they routinely operate across scales. Specifically, the interactions between host immune molecules and pathogens determine their transmission at the population level, which in turn determines the spread of diseases across regions; in addition, a major feature of emerging infectious diseases is that they infect a wide variety of non-human hosts, complicating their control. Consequently, in order to effectively understand and control infectious diseases, researchers require integrated training in interdisciplinary, cross-scale approaches that span the full range of biological organization, from molecules to ecosystems. The proposed Infectious Diseases Across Scales Training Program (IDASTP) at Emory University is designed to provide such inter-disciplinary training. This program will partner with 30 faculty from multiple schools and departments to train a total of four graduate students each year, with each student obtaining two years of training. Students will be recruited from a total of ~19 training-eligible students in three graduate programs with exceptional strengths in infectious disease research related to immunology, population biology and public health. The most important component of training in these programs is research, first as part of laboratory rotations, then as part of the dissertation project. IDASTP trainees will obtain integrated training in cross-scale infectious disease research through interdisciplinary curricula and a course Integrating Study and Control of Infectious Disease Across Scales. They will also participate in a biweekly Infectious Disease Forum and an Annual Infectious Disease Symposium, presented by local and external infectious disease experts. Seminars and symposium will focus on the fundamentals of cross-scale interactions, control applications and career development, providing workshops and exposing students to cross-disciplinary career opportunities in academic and non-academic settings. Further integration of student training across scales is ensured by the formation of dissertation committees that include faculty with expertise in infectious disease research at different scales. The overall objective of this training program is to produce broadly trained and competitive scientists who use interdisciplinary and cross-scale approaches to better study and control infectious disease. Graduates from this program will have acquired: broad knowledge of cross-scale disease dynamics; in-depth knowledge of their field of research; the ability to effectively develop research projects, grant proposals, presentations and publications; and an appreciation of the career trajectories available to infectious disease doctorates. The implementation of this program at Emory University will attract and retain top-tier students and produce new cohorts of specialists who can effectively tackle infectious diseases by utilizing cross-disciplinary tool sets.