Infectious Diseases Across Scales Training Program

项目摘要 传染病仍然是人类痛苦和死亡的主要原因。虽然有很多研究和 培训的重点是在单一范围内(例如在宿主内或在人口一级)研究传染病， 在控制传染病方面的一大挑战是，它们经常在不同规模上运作。具体来说， 宿主免疫分子和病原体之间的相互作用决定了它们在种群中的传播。 这反过来又决定了疾病在各区域的传播；此外，新出现的 传染性疾病是它们感染各种各样的非人类宿主，使它们的控制变得复杂。 因此，为了有效地了解和控制传染病，研究人员需要综合 在跨学科、跨规模的方法方面进行培训，这些方法涵盖所有生物组织，包括 分子到生态系统。建议的跨规模传染病培训计划(IDASTP) 埃默里大学就是为了提供这种跨学科的培训而设计的。该项目将与30名教职员工合作 每年从多个学校和院系共培养4名研究生，每名学生 获得两年的培训。将在三年内从总共~19名符合培训条件的学生中招收学生 在与免疫学、人口学有关的传染病研究方面具有非凡优势的研究生课程 生物学和公共卫生。在这些项目中，培训最重要的组成部分是研究，首先作为一部分 实验室旋转，然后作为论文项目的一部分。IDASTP学员将接受综合培训 通过跨学科课程和一门综合研究和研究的课程进行跨尺度传染病研究 跨规模的传染病控制。他们还将参加每两周一次的传染病论坛 以及由本地和外部传染病专家主办的传染病年度研讨会。 研讨会和专题讨论会将集中讨论跨范围相互作用、控制应用和 职业发展，提供工作坊，让学生接触到跨学科的职业机会 学术和非学术环境。进一步整合不同规模的学生培训是由 成立学位论文委员会，其中包括在不同大学具有传染病研究专长的教师 比例。该培训计划的总体目标是培养训练有素、具有竞争力的科学家 使用跨学科和跨规模的方法来更好地研究和控制传染病。毕业于 该计划将获得：跨规模疾病动力学的广泛知识；深入了解其 研究领域；有效开发研究项目、拨款建议、演示文稿和 出版物；以及对传染病博士可获得的职业轨迹的欣赏。这个 在埃默里大学实施这一计划将吸引和留住顶尖学生，并产生新的 能够通过利用跨学科工具集有效地处理传染病的专家队伍。

Project Summary Infectious diseases continue to be a major cause of human suffering and mortality. While much research and training has focused on studying infectious disease at a single scale (e.g. within hosts or at the population level), a major challenge in the control of infectious diseases is that they routinely operate across scales. Specifically, the interactions between host immune molecules and pathogens determine their transmission at the population level, which in turn determines the spread of diseases across regions; in addition, a major feature of emerging infectious diseases is that they infect a wide variety of non-human hosts, complicating their control. Consequently, in order to effectively understand and control infectious diseases, researchers require integrated training in interdisciplinary, cross-scale approaches that span the full range of biological organization, from molecules to ecosystems. The proposed Infectious Diseases Across Scales Training Program (IDASTP) at Emory University is designed to provide such inter-disciplinary training. This program will partner with 30 faculty from multiple schools and departments to train a total of four graduate students each year, with each student obtaining two years of training. Students will be recruited from a total of ~19 training-eligible students in three graduate programs with exceptional strengths in infectious disease research related to immunology, population biology and public health. The most important component of training in these programs is research, first as part of laboratory rotations, then as part of the dissertation project. IDASTP trainees will obtain integrated training in cross-scale infectious disease research through interdisciplinary curricula and a course Integrating Study and Control of Infectious Disease Across Scales. They will also participate in a biweekly Infectious Disease Forum and an Annual Infectious Disease Symposium, presented by local and external infectious disease experts. Seminars and symposium will focus on the fundamentals of cross-scale interactions, control applications and career development, providing workshops and exposing students to cross-disciplinary career opportunities in academic and non-academic settings. Further integration of student training across scales is ensured by the formation of dissertation committees that include faculty with expertise in infectious disease research at different scales. The overall objective of this training program is to produce broadly trained and competitive scientists who use interdisciplinary and cross-scale approaches to better study and control infectious disease. Graduates from this program will have acquired: broad knowledge of cross-scale disease dynamics; in-depth knowledge of their field of research; the ability to effectively develop research projects, grant proposals, presentations and publications; and an appreciation of the career trajectories available to infectious disease doctorates. The implementation of this program at Emory University will attract and retain top-tier students and produce new cohorts of specialists who can effectively tackle infectious diseases by utilizing cross-disciplinary tool sets.