FDA NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimans

项目摘要-密苏里州公共卫生实验室（MSPHL） 密苏里州卫生和老年人服务部（DHSS），密苏里州公共卫生 实验室（MSPHL）建议支持国家抗生素耐药性监测 系统（NARMS）零售肉类监测计划，继续其目前的抽样零售 肉类和测试沙门氏菌和弯曲杆菌，肠球菌，气单胞菌，弧菌和 其他乳糖阳性细菌。取样和检测将按照 NARMS零售肉类监测实验室协议，包括全基因组测序和 上传数据。具体而言，包括80个零售肉类样本的加强抽样 将在密苏里州中部地区收集并每月进行测试。MSPHL将运送所有分离株 每月向FDA兽药中心（CVM）提交一次，并每月进行一次采样， 使用国家档案和记录管理处提供的电子记录表测试与国家档案和记录管理处的数据交换。数据 将与密苏里州卫生和社会保障部和当地公共卫生流行病学项目共享。成果 包括每年对960个零售肉类样本进行检测，这将导致 提交分离株;提高分离株和数据的数据质量、样本多样性和及时性 意见书。此外，还将使用测试和抗菌数据的共享和审查 通过流行病学项目检测食源性疾病的爆发， 调查;教育卫生和社会安全部管理人员、地方公共卫生官员和公众 对当前和新出现的健康危害;支持食品安全计划的认识， 公众中的抗菌素耐药性;分析趋势，为卫生和社会保障部管理提供信息， 协助制定政策;实验室将使用数据评估 测试结果和质量保证措施。 页1的1

Project Summary – Missouri State Public Health Laboratory (MSPHL) The Missouri Department of Health and Senior Services (DHSS), Missouri State Public Health Laboratory (MSPHL) proposes to support the National Antimicrobial Resistance Monitoring System (NARMS) Retail Meat Surveillance Program by continuing its current sampling of retail meats and testing for Salmonella and Campylobacter, Enterococcus, Aeromonas, Vibrio and other lactose positive bacteria. Sampling and testing will be performed as directed in the NARMS Retail Meat Surveillance Laboratory Protocol, including Whole Genome Sequencing and uploading of the data. Specifically, enhanced sampling consisting of eighty retail meat samples will be collected in the mid-Missouri area and tested monthly. The MSPHL will ship all isolates to the FDA Center for Veterinary Medicine (CVM) monthly, and perform monthly sample and testing data exchange with NARMS using the electronic log sheets provided by NARMS. Data will be shared with Missouri DHSS and local public health epidemiology programs. Outcomes include the testing of 960 retail meat samples annually, which will lead to increased numbers of isolates submitted; improved data quality, sample diversity and timeliness of isolate and data submissions. In addition, the sharing and review of testing and antimicrobial data will be used by epidemiology programs to detect food borne disease outbreaks and coordinate investigations; educate DHSS administrators, local public health officials and the general public on current and emerging health hazards; support food safety program awareness of antimicrobial resistance among the public; analyze for trends to inform DHSS management and assist with policy development; and data will be used by the laboratory to assess accuracy of testing results and quality assurance practices. Page 1 of 1