FDA NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimans

项目摘要-密苏里州公共卫生实验室(MSPHL) 密苏里州卫生和高级服务部(DHSS)密苏里州公共卫生部 实验室(MSPHL)建议支持国家抗菌素耐药性监测 NARMS系统(NARMS)零售肉类监测计划继续其目前的零售抽样 肉类和沙门氏菌、弯曲杆菌、肠球菌、气单胞菌、弧菌和 其他乳糖阳性细菌。抽样和测试将按照 NARMS零售肉类监测实验室方案，包括全基因组测序和 上传数据。具体地说，加强了80个零售肉类样本的抽样 将在密苏里州中部地区收集，每月进行测试。MSPHL将运送所有分离株 每月到FDA兽医中心(CVM)，每月进行样品和 使用NARMS提供的电子日志表测试与NARMS的数据交换。数据 将与密苏里州DHSS和当地公共卫生流行病学项目共享。结果 包括每年检测960个零售肉类样本，这将导致增加 提交的分离物；提高了数据质量、样本多样性和隔离物和数据的及时性 意见书。此外，还将使用测试和抗菌数据的共享和审查 通过流行病学项目检测食源性疾病暴发并协调 调查；教育卫生署行政人员、当地公共卫生官员和公众 关于当前和新出现的健康危害；支持食品安全计划意识 公众中的抗菌素耐药性；分析趋势，以告知卫生与公众服务部管理层和 协助制定政策；实验室将使用数据来评估 测试结果和质量保证措施。 第1页，共1页

Project Summary – Missouri State Public Health Laboratory (MSPHL) The Missouri Department of Health and Senior Services (DHSS), Missouri State Public Health Laboratory (MSPHL) proposes to support the National Antimicrobial Resistance Monitoring System (NARMS) Retail Meat Surveillance Program by continuing its current sampling of retail meats and testing for Salmonella and Campylobacter, Enterococcus, Aeromonas, Vibrio and other lactose positive bacteria. Sampling and testing will be performed as directed in the NARMS Retail Meat Surveillance Laboratory Protocol, including Whole Genome Sequencing and uploading of the data. Specifically, enhanced sampling consisting of eighty retail meat samples will be collected in the mid-Missouri area and tested monthly. The MSPHL will ship all isolates to the FDA Center for Veterinary Medicine (CVM) monthly, and perform monthly sample and testing data exchange with NARMS using the electronic log sheets provided by NARMS. Data will be shared with Missouri DHSS and local public health epidemiology programs. Outcomes include the testing of 960 retail meat samples annually, which will lead to increased numbers of isolates submitted; improved data quality, sample diversity and timeliness of isolate and data submissions. In addition, the sharing and review of testing and antimicrobial data will be used by epidemiology programs to detect food borne disease outbreaks and coordinate investigations; educate DHSS administrators, local public health officials and the general public on current and emerging health hazards; support food safety program awareness of antimicrobial resistance among the public; analyze for trends to inform DHSS management and assist with policy development; and data will be used by the laboratory to assess accuracy of testing results and quality assurance practices. Page 1 of 1