INFANT COGNITIVE AND EEG DEVELOPMENT--BASIC PROCESSES

婴儿认知和脑电图发育——基本过程

• 批准号: 2200084
• 负责人: Nathan A Fox
• 金额: $ 14.37万
• 依托单位: UNIV OF MARYLAND, COLLEGE PARK
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-07-15 至 1997-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2200084
• 关键词: brain electrical activity; child behavior; child psychology; cognition; electroencephalography; emotions; human subject; infant human (0-1 year); language development; longitudinal human study; neocortex; neuropsychology; performance; preschool child (1-5); stimulus /response; videotape /videodisc

Recent advances in behavioral neuroscience research have permitted investigation of the relations between developing areas of the neocortex and emerging behavioral skills. There is evidence which suggests that while the frontal cortex is among the last areas of the brain to mature, it may subserve important functions during the period of infancy. One potential method for exploring brain/behavior relations is the measurement of scalp recorded brain electrical activity (EEG). Recent conceptual and computational advances have led to the use of the EEG as a measure of both regional development and of the emerging cortico-cortical connections. The purpose of the present study is to extend, into the second year of life, basic research on the maturation of the EEG and its relation to specific cognitive and language behaviors. It is our intention to chart developmental changes in a subset of cognitive and language competencies and to relate these changes to specific parameters of the EEG. We will complete a longitudinal study of 48 infants, beginning at age 14 months, and will see them every two months (14, 16, 18, 20, 22, and 24 months of age). At each age we will assess infant performance on tasks designed to tap frontally and non-frontally mediated competencies. In addition, we will assess the emergence of infant self-regulatory skills and have parents of the infants complete a standardized language assessment questionnaire. We will also record multi-lead EEG. Our aims include documenting changes in brain electrical activity-across the second year of life and investigating the associations between EEG changes and cognitive, language, and self-regulatory development. Enhanced understanding of these processes and their interrelationships will provide an important window into understanding cognitive-neuro development in the second year of life. It may also be of importance in understanding the cognitive, language, and self-regulatory development of atypical populations.

行为神经科学研究的最新进展使 大脑皮层发育区域间关系的研究 和新兴的行为技能。有证据表明 虽然额叶皮质是大脑中最后成熟的区域之一， 它可能会在婴儿期发挥重要的功能。一 探索大脑/行为关系的潜在方法是测量 头皮记录的脑电活动(EEG)。最近的概念和 计算技术的进步使得脑电波被用来衡量两者 区域发展和新出现的皮质-皮质连接。 本研究的目的是延长到#年的第二年 生命、脑电成熟的基础研究及其与脑电的关系 特定的认知和语言行为。我们的意图是绘制一张 认知和语言能力子集的发展变化 并将这些变化与脑电的特定参数相关联。我们会 完成一项对48名婴儿的纵向研究，从14个月大开始， 每两个月(14、16、18、20、22和24个月)见他们一次 年龄)。在每个年龄段，我们都会评估婴儿在任务中的表现 开发正面和非正面中介能力。此外，我们 将评估婴儿自我调节能力的出现，并拥有 婴儿的父母完成了标准化的语言评估 问卷调查。我们还将记录多导联脑电。我们的目标包括 记录脑电活动的变化-跨越第二年 并研究脑电变化和认知之间的联系， 语言和自律能力的发展。加深了对这些问题的理解 进程及其相互关系将提供一个重要的窗口 在生命的第二年理解认知神经的发育。 它也可能对理解认知、语言和 非典型人群的自我调节发展。