PHYSICAL TRAINING AND BLOOD PRESSURE IN HIGH RISK YOUTHS

拟议项目的长远目标是阐明 身体活动与心血管健康之间的关系 不同种族、性别和健康状况的儿童。 有两 明确的目标。 第一个是检验假设， 体育锻炼（PT）将降低血压，在休息和反应 前额寒冷和运动压力，在8-9奥尔兹谁是高， 血压和身体肥胖。 受试者将平均分配 性别、压力和身体肥胖。 受试者将平均分配 性别和种族（黑人/白色）。 静息和反应性血液 压力与左心室质量相关， 未来的原发性高血压 潜在的血流动力学调节因子 血压，心输出量，总外周阻力， 用心阻抗描记术测量以探索血流动力学机制 通过这种方式，训练对血压和左心室功能产生了有利的影响。 心室质量 第二个目的是检验物理学的假设， 通过双能X射线测量，训练将减少体脂百分比 吸收测定法（DEXA）。 在血压和肥胖方面都超过第70百分位的儿童将 根据种族和性别随机分配参加体育训练， 或候补名单对照组。 体能训练组经过 经过4个月的培训，所有受试者都将接受重新测试，这些数据将 用于检验主要假设。 最初的控制对象将 然后进行4个月的体能训练，之后他们将 重新测试。 第二阶段的数据将添加到 最初的体能训练小组，以探索训练与 性别和种族。 最初的体能训练组将被带到 回4个月后停止训练，看看引起的变化 是可逆的。 为了记录刺激， 在训练过程中，将监测心率。 到 观察完整实验室测试会话之间的变化的时间过程， 每月测量皮褶厚度和静息血压。 饮食和 自由生活体力活动将被评估，以帮助解释变化， 身体成分 有氧健身将通过跑步机测试进行测量， 最大耗氧量

The proposed project has the long-term objective of elucidating the relationship between physical activity and cardiovascular health in children varying in ethnicity, gender and health status. There are two specific aims. The first is to test the hypothesis that controlled physical training (PT) will reduce blood pressure, at rest and in reaction to forehead cold and exercise stressors, in 8-9 year olds who are high in both blood pressure and body fatness. Subjects will be divided equally on gender and pressure and body fatness. Subjects will be divided equally on gender and ethnicity (black/white). Both resting and reactive blood pressure are correlated with left ventricular mass and are predictive of future essential hypertension. The underlying hemodynamic regulators of blood pressure, cardiac output the total peripheral resistance, will be measured with impedance cardiography to explore hemodynamic mechanisms through which training has a favorable influence on blood pressure and left ventricular mass. The second aim is to test the hypothesis that physical training will reduce percent body fat, as measured with dual energy x-ray absorptiometry (DEXA). Children above the 70th percentile in both blood pressure and fatness will be randomly assigned, within ethnicity and gender, to a physical training or waiting list control group. After the physical training group undergoes 4 months of training, all subjects will be retested and these data will be used to test the primary hypotheses. The initial control subjects will then perform 4 months of physical training, after which they will be retested. The data from this second phase will be added to the data of the initial physical training group to explore interactions of training with gender and ethnicity. The initial physical training group will be brought back 4 months after cessation of training to see of the changes elicited by the training are reversible. To document the stimulation provided by the training, heart rate will be monitored during training sessions. To observe the time course of changes between the full lab testing sessions, skinfolds and resting blood pressure will be measured monthly. Diet and free living physical activity will be assessed to help explain changes in body composition. Aerobic fitness will be measured with treadmill tests of maximal oxygen consumption.