ANALYSIS OF MOLLUSCAN FAUNAS AND ASIAN SCHISTOSOMIASIS

软体动物区系与亚洲血吸虫病的分析

• 批准号: 3444440
• 负责人: GEORGE M DAVIS
• 金额: $ 10.15万
• 依托单位: THE ACADEMY OF NATURAL SCIENCES OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-02-07 至 1989-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3444440
• 关键词: China; Gastropoda; India; communicable disease transmission; evolution; histology; host organism interaction; schistosomiasis; southeast Asia; species difference; statistics /biometry

It is a major new discovery to find that gastropod taxa of the Pomatiopsidae, sub-family Triculinae, tribe Triculini transmit schistosomes infecting man in Asia. Tricula aperta transmits Schistosoma mekongi of the Mekong River; Robertsiellla kaporensis transmits Schistosoma sp. in central Malaysia (Davis, 1979, 1980; Davis and Greer, 1980). Phylogenetic assessments using classical means, cladistic methods, and techniques of multivariate analysis with ordination by nonmetric multidimensional scaling have shown that of 1,000 species of hydrobioid snails (worldwide), the capacity to transmit Asian schistosoma infecting man is restricted to the family Pomatiopsidae, the subfamily Pomatiopsinae, and the tribe Triculini of the Triculinae. The discovery of Robertsiella and the Malaysian schistosome (Davis and Greer, 1980) strengthens my hypothesis on the origin and evolution of Asian Schistosoma involving over 100 million years time and introduction to Asia via the Indian Plate. The direction of evolution is from India to the headwaters of the Mekong and Yangtze rivers and subsequently down evolving river systems (Davis, 1979, 1980). Specific objectives of this proposal are 1) to continue to study nominal species of Tricula and related taxa throughout their ranges (India, Burma, China, continental S.E. Asia, Philippines), 2) to continue to analyze the systematics and ecology of Triculinae of the Mekong River. By invitation of the Institute of Parasitic Diseases, Chinese Academy of Medical Sciences, Shanghai, work will commence in Yunnan, China on the Triculinae of China. Methods will involve detailed anatomy, ecological-microhabitat assessment, paleontological/geological data, zoogeographical analyses, and multivariate and cladistic techniques for phyletic analyses.

这是一项重大的新发现，它发现了腹足类的分类群 Pomatiopsidae，Tereinae亚科，Tereini部落传播血吸虫 在亚洲感染人类。腹侧沟吸虫传播日本血吸虫 湄公河；卡波罗伯氏菌传播血吸虫sp.位於中环的 马来西亚(Davis，1979,1980；Davis和Greer，1980)。系统发育 使用经典方法、分支方法和技术的评估 基于非度量多维标度的排序多元分析 研究表明，在全球1000种水生生物蜗牛中， 传播亚洲血吸虫感染人类的能力仅限于 Pomatiopsidae科、Pomatiopsinae亚科和Tousini部落 小蜂亚科的。罗伯特氏菌和马来丝虫的发现 血吸虫(Davis和Greer，1980)强化了我关于血吸虫起源的假设 亚洲血吸虫的演化涉及1亿多年的时间 并通过印度板块介绍亚洲。进化的方向 从印度到湄公河和长江的源头，以及 随后向下游演变的河流系统(Davis，1979,1980)。特定的 这项建议的目标是：1)继续研究标称物种 在其分布范围内(印度，缅甸，中国， 大陆东南亚，菲律宾)，2)继续分析 标题湄公河小蜂亚科的系统学和生态学。应邀请 中国医学科学院寄生虫病研究所所长 上海科大工作将在云南开工，中国对曲霉亚科 中国的名字。方法将涉及详细的解剖，生态-微生境 评估、古生物/地质数据、动物地理分析和 用于系统学分析的多变量和分支技术。