ANALYSIS OF MOLLUSCAN FAUNAS AND ASIAN SCHISTOSOMIASIS

软体动物区系与亚洲血吸虫病的分析

• 批准号: 3565443
• 负责人: GEORGE M DAVIS
• 金额: $ 10.15万
• 依托单位: THE ACADEMY OF NATURAL SCIENCES OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-02-07 至 1989-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3565443
• 关键词: China; Gastropoda; India; communicable disease transmission; evolution; histology; host organism interaction; schistosomiasis; southeast Asia; species difference; statistics /biometry

It is a major new discovery to find that gastropod taxa of the Pomatiopsidae, sub-family Triculinae, tribe Triculini transmit schistosomes infecting man in Asia. Tricula aperta transmits Schistosoma mekongi of the Mekong River; Robertsiellla kaporensis transmits Schistosoma sp. in central Malaysia (Davis, 1979, 1980; Davis and Greer, 1980). Phylogenetic assessments using classical means, cladistic methods, and techniques of multivariate analysis with ordination by nonmetric multidimensional scaling have shown that of 1,000 species of hydrobioid snails (worldwide), the capacity to transmit Asian schistosoma infecting man is restricted to the family Pomatiopsidae, the subfamily Pomatiopsinae, and the tribe Triculini of the Triculinae. The discovery of Robertsiella and the Malaysian schistosome (Davis and Greer, 1980) strengthens my hypothesis on the origin and evolution of Asian Schistosoma involving over 100 million years time and introduction to Asia via the Indian Plate. The direction of evolution is from India to the headwaters of the Mekong and Yangtze rivers and subsequently down evolving river systems (Davis, 1979, 1980). Specific objectives of this proposal are 1) to continue to study nominal species of Tricula and related taxa throughout their ranges (India, Burma, China, continental S.E. Asia, Philippines), 2) to continue to analyze the systematics and ecology of Triculinae of the Mekong River. By invitation of the Institute of Parasitic Diseases, Chinese Academy of Medical Sciences, Shanghai, work will commence in Yunnan, China on the Triculinae of China. Methods will involve detailed anatomy, ecological-microhabitat assessment, paleontological/geological data, zoogeographical analyses, and multivariate and cladistic techniques for phyletic analyses.

这是一个重大的新发现， Pomatiopsidae，亚科，族Triculini传递 感染亚洲人 开放拟钉螺传播湄公河血吸虫， 湄公河;卡波罗贝氏菌在中部传播血吸虫属 马来西亚（Davis，1979，1980; Davis and Greer，1980）。 系统发育 评估使用经典的手段，分支方法，和技术， 非度量多维标度排序多变量分析 已经表明，在1,000种水生蜗牛（全世界）中， 传播亚洲疟原虫感染人类的能力仅限于 科Pomatiopsidae，亚科Pomatiopsinae，和部落Triculini 拟谷盗亚科的 Robertsiella的发现和马来西亚 戴维斯和格里尔，1980年）加强了我对起源的假设 亚洲血吸虫的进化，涉及一亿多年的时间 并通过印度板块传入亚洲 进化的方向 是从印度到湄公河和长江的源头， 随后向下演变的河流系统（Davis，1979，1980）。 具体 该提案的目标是：1）继续研究 分布区的拟谷孢属及相关分类群（印度、缅甸、中国、 大陆东南部亚洲，菲律宾），2）继续分析 标题湄公河拟步甲亚科的系统学和生态学。 应邀 中国医学科学院寄生虫病所 科学，上海，将在中国云南开始对拟步甲亚科的研究 中华 方法将涉及详细的解剖，生态微生境 评估、古生物学/地质学数据、动物地理学分析，以及 多变量和分支系统学技术用于系统分析。