FACTORS DETERMINING MAXIMAL EXERCISE PERFORMANCE IN MAN

我们最近在184个非耐力训练的非 来自BLSA的正常最大运动量的肥胖男性和女性 心电图显示，年龄相关的最大摄氧量下降明显 最大摄氧量（VO 2 max）根据总肌肉质量标准化后衰减 而不是体重。 这些结果表明， 与年龄相关的外周（与中央循环）因素 最大有氧运动能力降低。 一个密切相关的问题是， 老年人最大耗氧量（VO 2 max）增加 受过训练的男性相对于年龄匹配的同龄人的差异是介导的 主要是通过中枢与外周的适应性。 我们进行 放射性核素心室造影和VO 2测量 对8名耐力训练者（平均年龄= 65 加/减5年，跑台VO 2 max = 51加/减4 ml/kg，min） 男人

We have recently demonstrated in 184 non endurance trained non obese men and women from the BLSA with normal maximal exercise ECG's that the age-associated decline in VO2 max was markedly attenuated after VO2 max was normalized for total muscle mass instead of body weight. These results suggested an important role of peripheral (vs central circulatory) factors in the age-related reduction of maximal aerobic performance. A closely related issue is whether the well documented marked increase in maximal oxygen-consumption (VO2 max) of older endurance trained men relative to that of age-matched peers is mediated primarily by central versus peripheral adaptations. We performed radionuclide ventriculography and VO2 measurements during maximal upright bicycle ergometry in 8 endurance trained (mean age = 65 plus/minus 5 yr, treadmill VO2 max = 51 plus/minus 4 ml/kg, min) men.