MHCRC-PSYCHOENDOCRINOLOGY: CHILDREN AND ADULTS

MHCRC-心理内分泌学：儿童和成人

• 批准号: 3107040
• 负责人: ARTHUR J. PRANGE
• 金额: $ 128.13万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 1979
• 资助国家: 美国
• 起止时间: 1979-07-01 至 1997-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3107040
• 关键词: biomedical facility; human subject; mental disorders; neuroendocrine system; psychobiology

This application seeks funding for the 14th to 18th years, inclusive, of the NIMH CRC at UNC-Chapel Hill. The requested funds would allow the CRC to continue its evolution as a core-based center and to continue to strengthen its research in the cause and treatment of major mental disorders. These include mood disorders, alcoholism, anxiety disorder, schizophrenia, movement disorders, and the neural and mental consequences of HIV infection. The theoretical base for the proposed research is founded in psychoendocrinology. However, as interest and opportunity have allowed, the base has extended to other disciplines. Research is performed through the agency of five scientific programs: the Psychoendocrinology Program; the Psychopharmacology Program; the Psychoimmunology Program; the Psychophysiology Program; the Reproductive and Developmental Psychobiology Program. Each program consists of a set of interlocking relationships; some of these form bridges between programs. The work of the scientific programs and of selected start-up projects is supported by eight core groups; the Administrative Core; the Clinical Research Support Core; the Neurobehavioral Assessment Core; the Endocrine Assay Laboratory; the Psychoneuroimmunology Laboratory; the Bioanalytical Laboratory; the Data Management and Biostatistics Core; the Computer Support Core. Only the Neurobehavioral Assessment Core is new. It was nurtured within the Clinical Research Support Core until it had demonstrated its viability and its importance to the Center and was then split off. An outstanding asset of the Center is the Clinical Research Unit at Dorothea Dix Hospital, where patients can be housed for intensive and extensive study at no cost to the federal government. This facility, the wards of the Department of Psychiatry, and the General Clinical Research Center at UNC offer an outstanding nexus of opportunities for clinical investigations in psychiatric inpatients, outpatients, selected medical population, and health volunteers. The Administrative Committee within the Administrative Core is the main executive unit of the Center. It interfaces with the cores and the scientific programs on the one hand and on the other hand with the Department of Psychiatry, Dix Hospital, the General CRC and the Advisory Board of the Center. The Advisory Board, the Administrative Committee and all Center members meet in a full-day off-campus retreat each November. The Center has a major investment in training as well as in research. This has been enormously advanced by the funding in the UNC Department of Psychiatry of a NIMH Clinical Research Fellowship Training grant, in 1988.

这项申请寻求资助的第14至18年，包括， 北卡罗来纳大学教堂山分校的NIMH CRC。 申请的资金将使儿童权利委员会 继续发展成为一个核心中心， 加强对重大精神疾病病因及治疗的研究 紊乱 包括情绪障碍，酗酒，焦虑症， 精神分裂症，运动障碍，以及神经和精神后果 艾滋病毒感染。 所提出的研究的理论基础建立在 心理内分泌学 然而，由于兴趣和机会的允许， 基地已扩展到其他学科。 研究是通过 五个科学项目的代理机构：心理内分泌学项目; 精神药理学项目 生殖与发育心理生物学 程序. 每一个程序都由一组互锁关系组成; 其中一些在程序之间形成桥梁。 科学方案和选定的启动项目的工作是 由八个核心小组支持;行政核心;临床 研究支持核心;神经行为评估核心;内分泌 心理神经免疫学实验室;生物分析实验室 实验室;数据管理和生物统计学核心;计算机 支持核心。 只有神经行为评估核心是新的。 这是 在临床研究支持核心中培养，直到它 证明了它的可行性和它对中心的重要性， 分开了 中心的一项突出资产是临床研究单位， Dorothea Dix医院，病人可以在那里接受重症监护， 对联邦政府免费进行广泛的研究。 这个设施， 精神科病房和一般临床研究 中心提供了一个出色的机会，临床 调查精神科住院病人、门诊病人、选定的医疗 人口和卫生志愿者。 行政核心内的行政委员会是主要的 中心的执行单位。 它与内核和 一方面是科学计划，另一方面是 Dix医院精神病科、CRC总医院和咨询中心 董事会的中心。 咨询委员会、行政委员会和 所有中心成员每年11月在一个全天的校外务虚会。 该中心在培训和研究方面进行了大量投资。 这 已经在美国国防部的资助下得到了极大的推进， 1988年获得NIMH临床研究奖学金培训补助的精神病学。