MHCRC-PSYCHOENDOCRINOLOGY: CHILDREN AND ADULTS

本申请寻求第14至18年(含)的资金 北卡罗来纳大学教堂山的NIMH CRC。所要求的资金将允许儿童权利委员会 继续发展为以核心为基础的中心，并继续 加强对重大精神疾病病因及治疗的研究 精神错乱。这些疾病包括情绪障碍、酗酒、焦虑症、 精神分裂症、运动障碍及其神经和精神后果 艾滋病毒感染的可能性。 建议研究的理论基础建立在 心理内分泌学。然而，在兴趣和机会允许的情况下， 这个基础已经扩展到其他学科。研究通过以下方式进行 五个科学项目的代理机构：精神内分泌学项目； 精神药理学计划；心理免疫学计划； 心理生理学课程；生殖与发育心理生物学 程序。每个程序由一组联锁关系组成； 其中一些项目构成了项目之间的桥梁。 科学方案和选定的启动项目的工作是 由八个核心小组支持；行政核心；临床 研究支持核心；神经行为评估核心；内分泌 分析实验室；精神神经免疫学实验室；生物分析实验室 实验室；数据管理和生物统计核心；计算机 支持核心。只有神经行为评估核心是新的。确实是 在临床研究支持核心中得到培育，直到它 证明了它的可行性和它对中心的重要性，然后是 分头行动。 该中心的一项重要资产是位于 多萝西娅·迪克斯医院，病人可以在那里接受重症监护和治疗 广泛的研究，联邦政府不承担任何费用。这个设施， 精神科病房和普通临床研究 北卡罗来纳大学的中心为临床提供了出色的机会 精神科住院病人、门诊病人、部分内科病人的调查 人口和健康志愿者。 行政核心内部的行政委员会是主要的 中心的执行单位。它与内核和 一方面是科学计划，另一方面是 迪克斯医院精神病科，儿童权利中心和咨询 中心董事会。咨询委员会、行政委员会和 每年11月，中心所有成员都会在一次全天的校外静修活动中聚会。 该中心在培训和研究方面投入了大量资金。这 得到了北卡罗来纳州北卡罗来纳大学 NIMH临床研究奖学金培训基金的精神病学，1988年。

This application seeks funding for the 14th to 18th years, inclusive, of the NIMH CRC at UNC-Chapel Hill. The requested funds would allow the CRC to continue its evolution as a core-based center and to continue to strengthen its research in the cause and treatment of major mental disorders. These include mood disorders, alcoholism, anxiety disorder, schizophrenia, movement disorders, and the neural and mental consequences of HIV infection. The theoretical base for the proposed research is founded in psychoendocrinology. However, as interest and opportunity have allowed, the base has extended to other disciplines. Research is performed through the agency of five scientific programs: the Psychoendocrinology Program; the Psychopharmacology Program; the Psychoimmunology Program; the Psychophysiology Program; the Reproductive and Developmental Psychobiology Program. Each program consists of a set of interlocking relationships; some of these form bridges between programs. The work of the scientific programs and of selected start-up projects is supported by eight core groups; the Administrative Core; the Clinical Research Support Core; the Neurobehavioral Assessment Core; the Endocrine Assay Laboratory; the Psychoneuroimmunology Laboratory; the Bioanalytical Laboratory; the Data Management and Biostatistics Core; the Computer Support Core. Only the Neurobehavioral Assessment Core is new. It was nurtured within the Clinical Research Support Core until it had demonstrated its viability and its importance to the Center and was then split off. An outstanding asset of the Center is the Clinical Research Unit at Dorothea Dix Hospital, where patients can be housed for intensive and extensive study at no cost to the federal government. This facility, the wards of the Department of Psychiatry, and the General Clinical Research Center at UNC offer an outstanding nexus of opportunities for clinical investigations in psychiatric inpatients, outpatients, selected medical population, and health volunteers. The Administrative Committee within the Administrative Core is the main executive unit of the Center. It interfaces with the cores and the scientific programs on the one hand and on the other hand with the Department of Psychiatry, Dix Hospital, the General CRC and the Advisory Board of the Center. The Advisory Board, the Administrative Committee and all Center members meet in a full-day off-campus retreat each November. The Center has a major investment in training as well as in research. This has been enormously advanced by the funding in the UNC Department of Psychiatry of a NIMH Clinical Research Fellowship Training grant, in 1988.