PHYSIOLOGICAL AND CYTOCHEMICAL PATHOLOGY OF PARASITIC DISEASES

一种裂解型抗锥虫因子(ATF-II)的纯化研究 从细菌种，荧光假单胞菌，延续。一个 采用反相高压分离技术开发了提纯程序 高效液相色谱，是一项专利的主题 正在处理由美国专利复审的申请 办公室。结构的质谱学和核磁共振研究 正在继续对活性化合物进行表征。这个 化学结构的确定是研究前必不可少的。 合成是启动的，药理和毒理特性 使用克氏锥虫感染进行检查。

Studies on the purification of a lytic anti-trypanosomal factor (ATF-II) from the bacterial species, Pseudomonas fluorescens, were continued. A purification procedure was developed employing reversed-phase high performance liquid chromatography and was the subject of a patent application which is being processed for review by the U.S. Patent Office. Mass spectroscopic and NMR studies on the structural characterization of the active compound are being continued. The determination of chemical structure is essential before studies on synthesis are initiated and pharmacological and toxicological properties are examined employing Trypanosoma cruzi infections.