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CEREBROSPINAL FLUID OXYTOCIN IN SCHIZOPHRENIC AND CONTROL SUBJECT

CEREBROSPINAL FLUID OXYTOCIN IN SCHIZOPHRENIC AND CONTROL SUBJECT
精神分裂症患者和对照组受试者的脑脊液催产素
批准号：
3845380
负责人：
D GLOVINSKY
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF MENTAL HEALTH
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3845380
关键词：
antipsychotic agents cerebrospinal fluid human subject oxytocin radioimmunoassay schizophrenia

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中文摘要
翻译
临床前研究表明神经药理学之间存在联系
英文摘要
Preclinical studies have suggested a link between the neuropharmacology of oxytocin (OT) and changes in behavior, cognition, and neurochemistry associated with schizophrenia. To test these observations clinically, we measured the cerebrospinal fluid OT concentrations of 40 schizophrenic and 15 control subjects using a competitive radioimmunoassay. The CSF OT concentrations of neuroleptic-treated patients were not statistically different from those of the neuroleptic-withdrawn group. No significant differences were found between mean values of the schizophrenic group and the healthy group.
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