A NEW ERBIUM LASER AND INFRARED FIBER SYSTEM FOR LASER ANGIOPLASTY

用于激光血管成形术的新型铒激光器和红外光纤系统

• 批准号: 3942938
• 负责人: M B LEON
• 金额: --
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3942938
• 关键词: atherosclerosis; clinical biomedical equipment; coronary disorder; diagnostic catheterization; fiber optics; human tissue

This is a continuation of previous research experiments attempting to characterize the optimal laser source and transmitting optical fibers for intravascular precise microablative surgery. Over the past year, considerable additional work has helped to characterize the optimal lasing parameters for variable composition plaque ablation. In addition, substantive progress has been made in developing zirconium fluoride glass fibers to meet power transmission, flexibility, strength, and durability requirements. Catheter and fiber tip development is proceeding such that we have demonstrated high efficiency ablation of tissue in a wet field through flexible catheters using a 200 micron fiber filling a 1.5mm sapphire output window. These preliminary studies have demonstrated the feasibility of Er:YAG laser and zirconium fluoride fibers as a system for laser angioplasty.

这是先前研究实验的延续。 试图确定最佳的激光光源和 用于血管内精密测量的传输光纤 微消融手术。在过去的一年里，相当大的 更多的工作有助于确定最佳激光的特性 可变成分斑块消融的参数。在……里面 此外，在发展方面取得了实质性进展。 满足电力传输要求的氟化锆玻璃纤维， 灵活性、强度和耐久性要求。导尿管和 纤维尖端的开发正在进行中，因此我们有 展示了在湿场中对组织的高效消融 通过使用200微米纤维填充的柔性导管 1.5 mm蓝宝石输出窗口。这些初步研究已经 论证了Er：YAG激光器和锆粉的可行性 氟化物纤维作为激光血管成形术的系统。