课题基金 / 基金详情

STUDY OF FUNCTIONS INVOLVED IN GENETIC RECOMBINATION

STUDY OF FUNCTIONS INVOLVED IN GENETIC RECOMBINATION
基因重组相关功能的研究
批准号：
3964501
负责人：
M GELLERT
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3964501
关键词：
Bacillus subtilis DNA gyrase Escherichia coli adenosinetriphosphatase bacterial DNA bacterial genetics dichroism enzyme induction /repression enzyme structure enzyme substrate complex genetic manipulation genetic mapping genetic recombination molecular biology molecular cloning neutron diffraction nucleic acid sequence nucleic acid structure plasmids regulatory gene

项目摘要

项目成果

M GELLERT的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Complexes of DNA gyrase with defined DNA fragments from 127 to 256 base pairs in length have been studied by the method of electro-dichroism. The results suggest that DNA is wrapped around the enzyme in a single loop of 110 base pairs, with the entry and exit points close together. The rest of the DNA extends outward in two tails with an angle of about 120 degrees between them. In the presence of ATP or a nonhydrolyzable ATP analog, the tails are wrapped back and bound to the enzyme core. This process is considered to represent an intermediate stage in the supercoiling reaction of DNA gyrase. The complexes are also being studied by neutron scattering methods. Preliminary results are consistent with the model of a single turn of DNA bound to the enzyme.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
EFFECTS OF DNA SUPERCOILING ON THE TOPOLOGICAL PROPERTIES OF NUCLEOSOMES
STUDIES OF IMMUNOGLOBULIN GENE REARRANGEMENT
EFFECTS OF DNA SUPERCOILING ON THE TOPOLOGICAL PROPERTIES OF NUCLEOSOMES
EFFECTS OF DNA SUPERCOILING ON THE TOPOLOGICAL PROPERTIES OF NUCLEOSOMES
海外基金