课题基金 / 基金详情

MECHANISMS OF PHTHALATE ESTER TOXICITIES IN MAMMALIAN SPECIES

MECHANISMS OF PHTHALATE ESTER TOXICITIES IN MAMMALIAN SPECIES
哺乳动物中邻苯二甲酸酯的毒性机制
批准号：
3965202
负责人：
R L MELNICK
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3965202
关键词：
chemical carcinogenesis diethylhexylphthalate dosage environmental toxicology hepatotoxin plastics spermicide teratogens toxin metabolism zinc

项目摘要

项目成果

R L MELNICK的其他基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Phthalate esters are plasticizers incorporated into nearly all plastic materials. The biochemical and ultrastructural effects of di(2-ethylhexyl)phthalate (DEHP) and related chemicals are being studied to assess potential mechanisms of phthalate ester toxicity. Since DEHP and other phthalates are also male chemosterilants and teratogenic in mice, studies are being conducted to determine the role of zinc in the pathophysiology of these reproductive effects and to discern no-observed toxic effect levels.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
MECHANISM OF DI(2-ETHYLHEXYL)PHTHALATE HEPATOTOXICITY
BIOAVAILABILITY AND TOXICITY STUDIES OF MICROENCAPSULATED CHEMICALS
BIOAVAILABILITY AND TOXICITY STUDIES OF MICROENCAPSULATED CHEMICALS
MECHANISM OF DI(2-ETHYLHEXYL)PHTHALATE HEPATOTOXICITY