SERUM CHOLESTEROL VALUES OF THE NIH WHHL RABBIT

NIH WHHL 兔的血清胆固醇值

• 批准号: 3978279
• 负责人: D BARNARD
• 金额: --
• 依托单位: DIVISION OF RESEARCH SERVICES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3978279
• 关键词: animal colony; blood lipoprotein; cholesterol; disease /disorder model; hyperlipidemia; low density lipoprotein; triglycerides

The Veterinary Resources Branch, Division of Research Services established a Watanabe Heritable Hyperlipidemic Rabbit (WHHL) breeding colony to be used as a resource for investigators requiring the use of this animal model. The colony is being characterized for serum total cholesterol, cholesterol levels of the lipoprotein fractions and serum triglyceride levels. Blood is being collected from rabbits at the following ages; six weeks, three months, seven months, and one year. Total serum cholesterol values ranged from 310 to 1251 mg/dl with a mean of 828 mg/dl. The low density lipoprotein cholesterol values ranges from to 1185 mg/dl with a mean of 630 mg/dl. The serum triglyceride values ranged from 107 to 959 mg/dl with a mean of 394 mg/dl.

兽医资源分支，研究服务司成立 Watanabe遗传性高脂血症兔（WHHL）繁殖群， 用作需要使用该动物的研究者的资源 模型 对殖民地的血清总胆固醇进行表征， 脂蛋白组分和血清甘油三酯的胆固醇水平 程度. 从以下年龄的兔子中采集血液： 几周，三个月，七个月，一年。 血清总胆固醇 数值范围为310 - 1251 mg/dl，平均值为828 mg/dl。 低 密度脂蛋白胆固醇值范围为1185 mg/dl， 平均值为630 mg/dl。 血清甘油三酯值范围为107至959 mg/dl，平均值为394 mg/dl。