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AIDS RELATED PROTEINS--STRUCTURE AND FUNCTION

AIDS RELATED PROTEINS--STRUCTURE AND FUNCTION
艾滋病相关蛋白质——结构和功能
批准号：
5201985
负责人：
D R DAVIES
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5201985
关键词：
X ray crystallography crystallization enzyme structure human immunodeficiency virus 1 mutant nucleotidyltransferase protein structure function structural biology virus protein

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中文摘要
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英文摘要
The core domain of a soluble mutant of the HIV-1 integration protein has been crystallized and the crystal structure determined. The structure provides a platform for the design of inhibitors with antiviral properties. The enzyme has been shown to belong to a new superfamily of polynucleotidyl transferases.
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