AIDS RELATED PROTEINS--STRUCTURE AND FUNCTION

艾滋病相关蛋白质——结构和功能

• 批准号: 3876009
• 负责人: D R DAVIES
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3876009
• 关键词: CD4 molecule; X ray crystallography; antireceptor antibody; crystallization; enzyme inhibitors; enzyme structure; glycoproteins; human immunodeficiency virus; monoclonal antibody; protease inhibitor; protein structure function; ribonuclease III; virus protein

1) A HIV RNase H construct has been crystallized. X-ray diffraction studies on the crystals show very weak diffraction to low resolution only. 2) Small crystals of human soluble CD4 complexed with the antibody OKT4a Fab have been obtained.

1) HIV RNase H 构建体已结晶。 X 射线衍射研究 晶体上的衍射仅显示出非常弱的低分辨率。 2) 人可溶性 CD4 与抗体 OKT4a 复合的小晶体 已获得Fab。