Determining the impacts of epigenetic modifying drugs on germline programming and offspring health
Determining the impacts of epigenetic modifying drugs on germline programming and offspring health
批准号:
nhmrc : GNT1144887
负责人:
A/Pr David Ziegler
金额:
$86.39万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
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英文摘要
New drugs have been developed that inhibit specific enzymes that regulate epigenetic pathways in cells. These pathways significantly affect growth and development in offspring and may represent a risk to future children of patients taking the drug. This project will determine these risks and provide data for developing clinical guidelines for safe use of the drugs.
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Determining the impacts of epigenetic modifying drugs on germline programming and offspring health
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批准号:nhmrc : 1144887
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项目类别:Project Grants
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资助金额:$58.41万
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财政年份:2018
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负责人:A/Pr David Ziegler
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依托单位:
Optimising targeted polyamine depletion for treatment of childhood neuroblastoma and brain tumours
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批准号:nhmrc : GNT1125036
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项目类别:Project Grants
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资助金额:$92.82万
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财政年份:2017
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负责人:A/Pr David Ziegler
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依托单位:
Optimising targeted polyamine depletion for treatment of childhood neuroblastoma and brain tumours
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批准号:nhmrc : 1125036
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项目类别:Project Grants
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资助金额:$63.36万
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财政年份:2017
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负责人:A/Pr David Ziegler
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依托单位:
Targeted Inhibition of the FACT (Facilitates Chromatin Transcription) Complex as a Novel Therapeutic Approach in Aggressive Childhood Cancers
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批准号:nhmrc : GNT1085411
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项目类别:Project Grants
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资助金额:$99.07万
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财政年份:2015
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负责人:A/Pr David Ziegler
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依托单位:
Targeted Inhibition of the FACT (Facilitates Chromatin Transcription) Complex as a Novel Therapeutic Approach in Aggressive Childhood Cancers
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批准号:nhmrc : 1085411
-
项目类别:Project Grants
-
资助金额:$68.65万
-
财政年份:2015
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负责人:A/Pr David Ziegler
-
依托单位:
Targeted inhibition of polyamine synthesis for treatment of childhood neuroblastoma
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批准号:nhmrc : 1006487
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项目类别:NHMRC Project Grants
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资助金额:$38.45万
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财政年份:2011
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负责人:A/Pr David Ziegler
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依托单位:
国内基金
海外基金
IMPACTS站点土壤铝活化机制研究
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批准号:40273045
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项目类别:面上项目
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资助金额:32.0万元
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批准年份:2002
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负责人:张晓山
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依托单位: