Household Transmission and Immunity to SARS-CoV-2 among Paediatric Clients of a Primary Care Center in a Low-resource Community in Rio de Janeiro

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Our aim is to study the household transmission dynamics of SARS-CoV-2 in a slum in Rio de Janeiro, Brazil and to estimate the immunity of the study population against the new virus. We will examine and test a sample of children and their families for SARS-CoV-2.Recruitment will take place at a primary health clinic, located in one of the poorest neighbourhoods of the city. We will recruit children 0 to 13 years of age who are brought to the clinic to receive free vaccinations. With the written informed consent from the child's guardian, we will collect the study samples. Afterwards we will visit the child's home to collect samples of all residents, with four follow-up visits in the first month, every three months during the first year and twice in the second year. We hope to uncover the role of children in the disease transmission.