CHROMOSOME METABOLISM AND CANCER

染色体代谢与癌症

• 批准号: 2894421
• 负责人: MENG-CHAO H YAO
• 金额: $ 21.55万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-04-01 至 2001-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2894421
• 关键词: CHROMOSOME; METABOLISM; CANCER

This is a competitive renewal application for a program to train students to do basic research in the association between chromosome structure and cancer. In continuation of our past program, we are requesting stipends for four trainees at the postdoctoral level. In addition, we are requesting three stipends for training at the predoctoral level. The predoctoral stipend request is appropriate due to the Hutchinson Center's recent authorization to grant the Ph.D. degree in Molecular and Cellular Biology by the State of Washington Higher Education Coordinating Board (granted September 1, 1993). The Center also recently entered an affiliation agreement with the University of Washington (July 1, 1994) and began the first year of the joint Molecular and Cellular Biology Graduate Program with the entering class of September 1994. Training will be performed by a faculty of fourteen investigators, all of whom are members of the Basic Sciences Division of the Fred Hutchinson Cancer Research Center. Each faculty member is a recognized expert in his or her own field and has an extensive record of successful training at both the graduate and postgraduate levels. A strength of the program is the diversity of cancer-related model systems under study by the faculty, ranging from genetics of the cell cycle to the enzymology of transcript ion initiation and termination. Predoctoral trainees will be selected from the pool of high quality students admitted yearly to the graduate program. First year students initially rotate through three different laboratories at both the Hutchinson Center and the University before choosing a mentor with whom to do thesis research. Students whose interests are related to cancer will be given priority to be supported by the proposed program. Postdoctoral trainee are selected from a national pool of applicants. In addition to becoming immersed in their chosen research topic, both groups of trainees are encouraged to participate in the intellectual life of the Basic Sciences Division. This includes specialty journal clubs, joint laboratory meetings, and a regular series of seminars by outside speakers. In addition, trainees are expected to present their own findings at regular intervals, both in small group meetings as well as in a more formal weekly research seminar that is attended by the entire Division. This type of training has been shown to be effective in producing young investigators who are capable of independent, creative scientific research in the molecular basis of cancer.

这是一个有竞争力的更新应用程序的一个程序，以培养学生 对染色体结构和 癌 为了延续我们过去的计划，我们要求 为四名博士后级别的学员提供培训。 此外，我们在 申请三笔奖学金进行博士预科培训 的 博士前津贴的要求是适当的，由于哈钦森中心的 最近批准授予博士学位分子和细胞学学位 华盛顿州高等教育协调委员会 （1993年9月1日批准）。 该中心最近还进入了一个 与华盛顿大学的合作协议（1994年7月1日） 并开始了第一年的联合分子和细胞生物学 研究生课程与1994年9月的入学班。 培训将由14名研究人员组成的教师进行， 他们是弗雷德哈钦森基础科学部的成员 癌症研究中心。每一位教师都是公认的专家， 或她自己的领域，并有广泛的成功培训记录， 研究生和研究生两个层次。该计划的一个优势是 该学院正在研究的癌症相关模型系统的多样性， 从细胞周期的遗传学到转录物的酶学 离子起始和终止。 博士前培训生将从高质量的人才库中选拔 研究生课程每年录取的学生。一年级学生 最初在两个实验室的三个不同的实验室轮流进行， 哈钦森中心和大学在选择导师与谁 做论文研究 兴趣与癌症相关的学生 将优先得到拟议方案的支持。 博士后培训生是从国家申请者中挑选出来的。在 除了沉浸在他们选择的研究主题中，两组人都 的受训人员参加的知识生活， 基础科学部。这包括专业期刊俱乐部，联合 实验室会议，以及外部定期举办的一系列研讨会 扬声器.此外，预计学员将提出自己的 定期在小组会议以及 在一个更正式的每周研究研讨会上， 师.这种培训已被证明是有效的， 培养能够独立、有创造力、 癌症分子基础的科学研究。