TRAINING PROGRAM IN MOLECULAR CELL BIOLOGY OF CANCER

癌症分子细胞生物学培训项目

• 批准号: 6164122
• 负责人: JAMES H KEEN
• 金额: $ 30.51万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-05-10 至 2004-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6164122
• 关键词: TRAINING; PROGRAM; MOLECULAR; CELL; BIOLOGY

The approaches and paradigms of molecular cell biology and structural biology have been rewarding in relating structure and function at the molecular level to the behavior of the intact cell, either alone or as part of organ systems in the multi-cellular organism. Nowhere is this perspective more necessary or potentially more useful than in the multi- disciplinary approach that is required in the study of human cancer. The Training Program in the Molecular Cell Biology of Cancer utilizes selected faculty of the Kimmel Cancer Institute, a group of accomplished scientists who share related interests in defining the normal mechanisms of cellula function and growth control and their derangement in neoplasia. The goal of the Training program is to provide aspiring researchers with the training and experience necessary for him to launch careers as independent scientific investigators with an orientation toward research questions in human oncology. Predoctoral students in the Training Program will be drawn from those enrolled in the Molecular Pharmacology and Structural Biology Ph.D. Program, which has a major focus on molecular cell biology as it applies to human oncology. Predoctoral students must complete a rigorous series of graduate courses giving them a thorough background in biochemistry, molecular biology and cell biology. This didactic curriculum is then followed by more specialized courses both within the Ph.D. Program and available through the other Graduate Programs in the College of Graduate Studies of Thomas Jefferson University. Studies are required to complete three rotations in the laboratories of research preceptors with diverse interests and also present a series of seminars to the faculty. Research Advisory Committee and the supervisory, Graduate Studies Committee, the student may tailor his/her curriculum depending on prior experience or specific interests. Appointments to this Training Program are made no earlier than the conclusion of the first year of graduate study. The program of study leading to a Ph.D. degree is open to students who hold a Bachelor's degree from an accredited institution who wish to enter biomedical research without become a physician, as well as to individuals holding profession degrees (M.D., D.O., D.V.M. or D.D.S.) who wish to make academic careers as independent scientific investigators. Applicants must have a solid background in the biological and chemical sciences. Previous research experience is highly desirable. Only full-time students are accepted. Grade point average, GRE scores, letters of recommendation, statement of research interest and an interview are all important criteria for acceptance. Postdoctoral applicants must hold a Ph.D., M.D., D.O., D.D.S., or D.V.M. degree. Each trainee's program will depend of past research and educational experience. The goal of this Program is to develop highly trained, technically competent research scientists capable of performing and eventually directing research in the molecular cell biology of cancer.

分子细胞生物学和结构生物学的方法和范例在将分子水平上的结构和功能与完整细胞的行为（单独的或作为多细胞生物体中的器官系统的一部分）相关联方面是有益的。没有什么地方比在人类癌症研究中所需的多学科方法更需要这种观点或可能更有用。在癌症的分子细胞生物学的培训计划利用Kimmel癌症研究所，一组有成就的科学家谁在定义细胞功能和生长控制的正常机制和肿瘤的紊乱共享相关的利益选定的教师。培训计划的目标是为有抱负的研究人员提供必要的培训和经验，使他能够作为独立的科学调查人员开展职业生涯，并以人类肿瘤学的研究问题为导向。培训计划的博士预科生将从分子药理学和结构生物学博士生中选出。程序，其中有一个主要的重点是分子细胞生物学，因为它适用于人类肿瘤学。博士预科生必须完成一系列严格的研究生课程，使他们在生物化学，分子生物学和细胞生物学的全面背景。这种教学课程之后是更专业的课程，无论是在博士学位。计划和可通过其他研究生课程在托马斯杰斐逊大学研究生院。研究需要在具有不同兴趣的研究导师的实验室完成三次轮换，并向教师提供一系列研讨会。研究咨询委员会和监督，研究生学习委员会，学生可以根据以前的经验或具体利益定制他/她的课程。本培训计划的修改不早于研究生学习的第一年结束。攻读博士学位的课程。学位是开放给谁持有学士学位的学生从认可的机构谁希望进入生物医学研究没有成为一名医生，以及个人持有专业学位（医学博士，国防部，D.V.M.或D.D.S.）他们希望以独立的科学研究者的身份从事学术事业。申请人必须在生物和化学科学方面有坚实的背景。以前的研究经验是非常可取的。只接受全日制学生。平均成绩、GRE成绩、推荐信、研究兴趣陈述和面试都是录取的重要标准。博士后申请人必须持有博士学位，医学博士，国防部，D.D.S.，或DVM℃下每个学员的计划将取决于过去的研究和教育经验。该计划的目标是培养训练有素，技术能力强的研究科学家，能够执行并最终指导癌症的分子细胞生物学研究。