RESEARCH TRAINING IN GASTROENTEROLOGY

该计划的目的是为致力于调查胃肠病学事业的年轻调查人员提供培训。该计划将每年招收两名学员，进行为期两三年的研究培训。受训者将是医学博士，医学博士，已经完成临床和/或研究生培训，正在寻求胃肠病学研究培训的博士。培训将主要包括指导研究，将提供大量的实践经验，研究方法和实验设计，数据收集技术，数据解释，包括适当的统计分析和研究结果的准备，以供演示和出版。学员将由经验丰富的研究导师监督，他们具有广泛的兴趣和专业知识，从基础细胞和分子生物学到临床研究。一个由拉蒙博士、默丘里奥博士、特霍斯特博士和一两名其他培训教员组成的培训委员会将监督每个学员的研究进展。还将提供丰富的教学课程、研讨会和会议。可用于培训的主要研究领域包括：1）肠道炎症和感染的病理生理学，2）。炎症性肠病的免疫机制，3.）肠癌中的细胞和分子异常，4.）肠糖蛋白的结构和功能，5。肝脏和肠道疾病中的受体生物学和6.）胃肠道的粘膜免疫。该培训计划将利用GI部门和医学，外科和病理学系其他实验室的杰出GI研究基地。该培训计划还将受益于该医院组织良好和资金充足的临床研究中心，以及两个消化疾病中心的临近，一个在哈佛医学院，另一个在马萨诸塞州总医院。

The purpose of this program is to provide training for young investigators committed to a career in investigative gastroenterology. The program will recruit two trainees per year for two or three years of research training. Trainees will be MDs, MD-PhDs who have finished their clinical and/or graduate training and are seeking research training in gastroenterology. Training will consist primarily of mentored research that will provide intense hands-on experience in research methods and experimental design, techniques of data collection, data interpretation including appropriate statistical analysis and preparation of research results for presentation and publication. Trainees will be supervised by experienced research mentors with a wide range of interests and expertise from basic cellular and molecular biology to clinical research. A training committee composed of Drs. Lamont, Mercurio, Terhorst, and one or two other training faculty will monitor each trainee's research progress. A rich menu of didactic courses, seminars and conferences will also be provided. The major areas of research available for training include: 1) Pathophysiology of intestinal inflammation and infection, 2.) Immune mechanisms of inflammatory bowel disease, 3.) Cellular and molecular abnormalities in intestinal cancer, 4.) Structure and function of intestinal glycoproteins, 5.) Receptor biology in hepatic and intestinal diseases and 6.) Mucosal immunity of the gastrointestinal tract. The training program will take advantage of the outstanding GI research base within the GI division and in other laboratories in the Department of Medicine, Surgery and Pathology. The training program will also benefit from the availability of a well organized and funded Clinical Research Center at this hospital, as well as the close proximity of two Digestive Disease Centers, one at Harvard Medical School and a second at Massachusetts General Hospital.