Research Training in Gastroenterology

胃肠病学研究培训

• 批准号: 7258814
• 负责人: JOHN THOMAS LAMONT
• 金额: $ 20.43万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7258814
• 关键词: Gastroenterology; Research Training

DESCRIPTION (provided by applicant): This is a competing continuation application for renewal of a training program in gastroenterology that was first funded in 1999. The objectives of this program are to provide research training for young investigators committed to a career in investigative gastroenterology or allied fields. The types of research training include basic, translational or clinical research, or combinations of these. Trainees may be MDs, MD-PhDs or PhDs who have finished clinical or graduate training and are seeking further research training in gastroenterology. The training period will last two to three years. Training will consist primarily of mentored research that will provide intense hands-on experience in research methods and experimental design, techniques of data collection, data interpretation including appropriate statistical analysis and preparation of research results for presentation and publication. An extensive menu of didactic courses, workshops, seminars and conferences will also be available. Trainees will be supervised by experienced research mentors with a wide range of interests and expertise from basic cellular and molecular biology to clinical research. A training committee composed of Drs. Lamont, Kelly, Afdhal, and Terhorst and one or two other training faculty will monitor each trainee's research progress. An extensive menu of didactic courses, workshops, seminars and conferences will also be available. The major areas of research available for training include: 1.) Pathophysiology of intestinal inflammation and infection, 2.) Immune mechanisms of bowel disease, 3.) Cellular and molecular abnormalities in intestinal cancer, 4.) Enteric infections, 5.) Receptor biology in hepatic and intestinal diseases, 6.) Mucosal immunity of the gastrointestinal tract, 7.) Hepatic fibrosis, 8.) Regulation of nutrient intake, 9.) Vaccine development and 10.) Genetic factors in GI diseases. The training program will take advantage of the outstanding GI research base within the GI Division and in other laboratories in the Departments of Medicine and Surgery. The training program will also benefit from the availability of a well organized and funded Clinical Research Center at this medical center, as well as the close proximity of two Digestive Disease Centers, one at Harvard Medical School and a second at Massachusetts General Hospital.

描述（由申请人提供）： 这是一项竞争性延续申请，旨在更新 1999 年首次资助的胃肠病学培训计划。该计划的目标是为致力于胃肠病学研究或相关领域职业的年轻研究人员提供研究培训。研究培训的类型包括基础研究、转化研究或临床研究，或这些的组合。学员可以是医学博士、医学博士-博士或已完成临床或研究生培训并正在寻求胃肠病学进一步研究培训的医学博士、医学博士-博士或博士。培训期将持续两到三年。培训将主要包括指导性研究，将提供研究方法和实验设计、数据收集技术、数据解释（包括适当的统计分析）以及准备用于演示和出版的研究结果方面的丰富实践经验。还将提供广泛的教学课程、讲习班、研讨会和会议。学员将受到经验丰富的研究导师的监督，他们具有从基础细胞和分子生物学到临床研究的广泛兴趣和专业知识。由博士组成的培训委员会。拉蒙特、凯利、阿夫达尔和特霍斯特以及其他一到两名培训教员将监督每位学员的研究进展。还将提供广泛的教学课程、讲习班、研讨会和会议。可供培训的主要研究领域包括：1.) 肠道炎症和感染的病理生理学，2.) 肠道疾病的免疫机制，3.) 肠癌的细胞和分子异常，4.) 肠道感染，5.) 肝脏和肠道疾病中的受体生物学，6.) 胃肠道粘膜免疫，7.) 肝纤维化，8.) 肝纤维化的调节 营养摄入，9.) 疫苗开发和 10.) 胃肠道疾病的遗传因素。该培训计划将利用胃肠病科以及内科和外科系其他实验室的杰出胃肠病研究基地。该培训计划还将受益于该医疗中心组织良好且资金充足的临床研究中心，以及邻近的两个消化疾病中心，一个位于哈佛医学院，另一个位于马萨诸塞州总医院。