RESEARCH TRAINING IN GASTROENTEROLOGY

该计划的目的是为致力于研究胃肠病学职业的年轻研究人员提供培训。该计划将每年招募两名实习生，进行两三年的研究培训。受训者将是医学博士和医学博士，他们已完成临床和/或研究生培训，并正在寻求胃肠病学方面的研究培训。培训将主要包括指导研究，这些研究将在研究方法和实验设计、数据收集技术、数据解释(包括适当的统计分析)以及准备提交和出版研究结果方面提供丰富的实践经验。受训者将由经验丰富的研究导师指导，这些导师具有从基础细胞和分子生物学到临床研究的广泛兴趣和专业知识。由Lamont博士、Mercurio博士、Terhorst博士和一两个其他培训人员组成的培训委员会将监督每个受训人员的研究进展。还将提供丰富的教学课程、研讨会和会议菜单。可供培训的主要研究领域包括：1)肠道炎症和感染的病理生理学；2)炎症性肠病的免疫机制。4.肠癌的细胞和分子异常。肠糖蛋白的结构和功能，5)受体生物学在肝脏和肠道疾病中的作用和6。胃肠道的粘膜免疫。培训计划将利用GI部门和内科、外科和病理部其他实验室的优秀GI研究基地。培训计划还将受益于这家医院组织良好、资金充足的临床研究中心，以及两个消化系统疾病中心，一个在哈佛医学院，另一个在马萨诸塞州总医院。

The purpose of this program is to provide training for young investigators committed to a career in investigative gastroenterology. The program will recruit two trainees per year for two or three years of research training. Trainees will be MDs, MD-PhDs who have finished their clinical and/or graduate training and are seeking research training in gastroenterology. Training will consist primarily of mentored research that will provide intense hands-on experience in research methods and experimental design, techniques of data collection, data interpretation including appropriate statistical analysis and preparation of research results for presentation and publication. Trainees will be supervised by experienced research mentors with a wide range of interests and expertise from basic cellular and molecular biology to clinical research. A training committee composed of Drs. Lamont, Mercurio, Terhorst, and one or two other training faculty will monitor each trainee's research progress. A rich menu of didactic courses, seminars and conferences will also be provided. The major areas of research available for training include: 1) Pathophysiology of intestinal inflammation and infection, 2.) Immune mechanisms of inflammatory bowel disease, 3.) Cellular and molecular abnormalities in intestinal cancer, 4.) Structure and function of intestinal glycoproteins, 5.) Receptor biology in hepatic and intestinal diseases and 6.) Mucosal immunity of the gastrointestinal tract. The training program will take advantage of the outstanding GI research base within the GI division and in other laboratories in the Department of Medicine, Surgery and Pathology. The training program will also benefit from the availability of a well organized and funded Clinical Research Center at this hospital, as well as the close proximity of two Digestive Disease Centers, one at Harvard Medical School and a second at Massachusetts General Hospital.